Investigating the genetic architecture of noncognitive skills using GWAS-by-subtraction
Little is known about the genetic architecture of traits affecting educational attainment other
than cognitive ability. We used genomic structural equation modeling and prior genome …
than cognitive ability. We used genomic structural equation modeling and prior genome …
[HTML][HTML] PUMAS: fine-tuning polygenic risk scores with GWAS summary statistics
Polygenic risk scores (PRSs) have wide applications in human genetics research, but often
include tuning parameters which are difficult to optimize in practice due to limited access to …
include tuning parameters which are difficult to optimize in practice due to limited access to …
Genetic “general intelligence,” objectively determined and measured
It has been known for 115 years that, in humans, diverse cognitive traits are positively
intercorrelated; this forms the basis for the general factor of intelligence (g). We directly test …
intercorrelated; this forms the basis for the general factor of intelligence (g). We directly test …