Nanopore detection of metal ions: current status and future directions

GM Roozbahani, X Chen, Y Zhang, L Wang… - Small …, 2020 - Wiley Online Library
In this review, recent research efforts that aimed at developing nanopore sensors for
detection of metal ions, which play a crucial role in environmental safety and human health …

Sensing proteins through nanopores: fundamental to applications

A Oukhaled, L Bacri, M Pastoriza-Gallego… - ACS chemical …, 2012 - ACS Publications
Proteins subjected to an electric field and forced to pass through a nanopore induce
blockades of ionic current that depend on the protein and nanopore characteristics and …

DNA nanotechnology assisted nanopore-based analysis

T Ding, J Yang, V Pan, N Zhao, Z Lu, Y Ke… - Nucleic acids …, 2020 - academic.oup.com
Nanopore technology is a promising label-free detection method. However, challenges exist
for its further application in sequencing, clinical diagnostics and ultra-sensitive single …

Single-molecule studies of intrinsically disordered proteins

M Brucale, B Schuler, B Samorì - Chemical reviews, 2014 - ACS Publications
The last 15 years saw a dramatic increase in the number of published papers exposing
research related to the concept of protein disorder and a concomitant increase in the …

Single molecule analysis by biological nanopore sensors

YL Ying, C Cao, YT Long - Analyst, 2014 - pubs.rsc.org
Nanopore sensors provide a highly innovative technique for a rapid and label-free single
molecule analysis, which holds a great potential in routing applications. Biological …

NanoporeBased, Rapid Characterization of Individual Amyloid Particles in Solution: Concepts, Challenges, and Prospects

J Houghtaling, J List, M Mayer - Small, 2018 - Wiley Online Library
Aggregates of misfolded proteins are associated with several devastating
neurodegenerative diseases. These socalled amyloids are therefore explored as …

A biosensing expedition of nanopore: a review

A Nehra, S Ahlawat, KP Singh - Sensors and Actuators B: Chemical, 2019 - Elsevier
The fascinating domain of nanoscience presents vast opportunities and challenges for
developing myriad nanometer-scale biosensing systems. The advent of the nanopore and …

Peptide-mediated nanopore detection of uranyl ions in aqueous media

GM Roozbahani, X Chen, Y Zhang, R Xie, R Ma… - ACS …, 2017 - ACS Publications
Uranium is one of the most common radioactive contaminants in the environment. As a
major nuclear material in production, environmental samples (like soil and groundwater) can …

Nanopore detection of copper ions using a polyhistidine probe

G Wang, L Wang, Y Han, S Zhou, X Guan - Biosensors and Bioelectronics, 2014 - Elsevier
We report a stochastic nanopore sensing method for the detection of Cu 2+ ions. By
employing a polyhistidine molecule as a chelating agent, and based on the different …

Real-time label-free measurement of HIV-1 protease activity by nanopore analysis

L Wang, Y Han, S Zhou, X Guan - Biosensors and Bioelectronics, 2014 - Elsevier
A label-free method for the measurement of the activity of HIV-1 protease is developed by
real-time monitoring of the cleavage of a peptide substrate by HIV-1 protease in a nanopore …