[HTML][HTML] Ovariectomized rat model of osteoporosis: a practical guide

N Yousefzadeh, K Kashfi, S Jeddi, A Ghasemi - EXCLI journal, 2020 - ncbi.nlm.nih.gov
Osteoporosis affects about 200 million people worldwide and is a silent disease until a
fracture occurs. Management of osteoporosis is still a challenge that warrants further studies …

Osteoporosis therapies and their mechanisms of action

B Kim, YJ Cho, W Lim - Experimental and therapeutic …, 2021 - spandidos-publications.com
Osteoporosis is a common disease that affects millions of patients worldwide and is most
common in menopausal women. The main characteristics of osteoporosis are low bone …

Therapeutic anabolic and anticatabolic benefits of natural Chinese medicines for the treatment of osteoporosis

J He, X Li, Z Wang, S Bennett, K Chen, Z Xiao… - Frontiers in …, 2019 - frontiersin.org
Osteoporosis is a bone disease characterized by increasing osseous fragility and fracture
due to the reduced bone mass and microstructural degradation. Primary pharmacological …

[PDF][PDF] Pharmacological agents and natural compounds: available treatments for osteoporosis.

M Martiniakova, M Babikova, R Omelka - Journal of Physiology & …, 2020 - jpp.krakow.pl
Osteoporosis, a systemic skeletal disease characterized by a decrease in bone mass and
deterioration of bone structure leading to an increased risk of fragility fractures, represents …

[HTML][HTML] Osteoblastic and anti-osteoclastic activities of strontium-substituted silicocarnotite ceramics: In vitro and in vivo studies

J Zeng, J Guo, Z Sun, F Deng, C Ning, Y Xie - Bioactive materials, 2020 - Elsevier
Osteoporosis bone defect is a refractory orthopaedic disease which characterized by
impaired bone quality and bone regeneration capacity. Current therapies, including …

Zeolitic Imidazolate Framework‑8 (ZIF-8) modified titanium alloy for controlled release of drugs for osteoporosis

M Sandomierski, M Jakubowski, M Ratajczak… - Scientific Reports, 2022 - nature.com
The aim of this work was to prepare a biocompatible implant material that enables the
release of drug for osteoporosis—risedronate. To achieve this goal, a titanium implant …

Loading-driven PI3K/Akt signaling and erythropoiesis enhanced angiogenesis and osteogenesis in a postmenopausal osteoporosis mouse model

A Abdurahman, X Li, J Li, D Liu, L Zhai, X Wang… - Bone, 2022 - Elsevier
Bone vasculature influences osteogenesis and haematopoiesis in the bone
microenviroment. Mechanical loading has been shown to stimulate the formation of …

Bone regeneration in osteoporosis: opportunities and challenges

D Patel, S Wairkar - Drug Delivery and Translational Research, 2023 - Springer
Osteoporosis is a bone disorder characterised by low bone mineral density, reduced bone
strength, increased bone fragility, and impaired mineralisation of bones causing an …

[HTML][HTML] The role of prunes in modulating inflammatory pathways to improve bone health in postmenopausal women

JJ Damani, MJ De Souza, HL VanEvery, NCA Strock… - Advances in …, 2022 - Elsevier
The prevalence of osteoporosis among women aged 50 y and older is expected to reach
13.6 million by 2030. Alternative nonpharmaceutical agents for osteoporosis, including …

LncRNA AK077216 promotes RANKLinduced osteoclastogenesis and bone resorption via NFATc1 by inhibition of NIP45

C Liu, Z Cao, Y Bai, C Dou, X Gong… - Journal of Cellular …, 2019 - Wiley Online Library
Osteoclasts derived from the monocyte/macrophage hematopoietic lineage regulate bone
resorption, a process balanced by bone formation in the continual renewal of the skeletal …