Flavonoids are plant bioactive compounds of great interest in nutrition and pharmacology,
due to their remarkable properties as antioxidant, anti-inflammatory, antibacterial, antifungal …

Plant exosome-like nanovesicles, being innately replete with bioactive lipids, proteins, RNA,
and other pharmacologically active molecules, offer unique morphological and …

Naringin and naringenin are the main bioactive polyphenols in citrus fruits, the consumption
of which is beneficial for human health and has been practiced since ancient times …

Naringenin, a citrus flavonoid that possesses various biological activities, has emerged as a
potential therapeutic agent for the management of a variety of diseases. Studies using cell …

Naringenin (NRG) is a polyphenolic phytochemical belonging to the class of flavanones and
is widely distributed in citrus fruits and some other fruits such as bergamot, tomatoes, cocoa …

The gut mucosal immune system is considered to play an important role in counteracting
potential adverse effects of food-derived antigens including nanovesicles. Whether …

Macrophages are critical mediators of the innate immune response against foreign
pathogens, including bacteria, physical stress, and injury. Therefore, these cells play a key …

Human tumor necrosis factor (TNF), first isolated by our group as an anticancer agent, has
been now shown to be a primary mediator of inflammation. Till today 19 different members of …

Inflammatory bowel disease (IBD) is characterized by chronic inflammation of the intestine
that compromises the patients' life quality and requires sustained pharmacological and …

Inflammatory bowel disease (IBD) represents chronic recurrent intestinal inflammation
resulting from various factors. Crohn's disease (CD) and ulcerative colitis (UC) have been …