Lignin degradation: microorganisms, enzymes involved, genomes analysis and evolution
Extensive research efforts have been dedicated to describing degradation of wood, which is
a complex process; hence, microorganisms have evolved different enzymatic and non …
a complex process; hence, microorganisms have evolved different enzymatic and non …
Lignin valorisation via enzymes: A sustainable approach
Lignin is the 3rd most abundant biopolymer surpassed by cellulose and hemicellulose and
is the most abundant aromatics resource available on earth for utilization by mankind. It was …
is the most abundant aromatics resource available on earth for utilization by mankind. It was …
Same substrate, many reactions: oxygen activation in flavoenzymes
Over time, organisms have evolved strategies to cope with the abundance of dioxygen on
Earth. Oxygen-utilizing enzymes tightly control the reactions involving O2 mostly by …
Earth. Oxygen-utilizing enzymes tightly control the reactions involving O2 mostly by …
The enigmatic reaction of flavins with oxygen
The reaction of flavoenzymes with oxygen remains a fascinating area of research because
of its relevance for reactive oxygen species (ROS) generation. Several exciting recent …
of its relevance for reactive oxygen species (ROS) generation. Several exciting recent …
The substrate oxidation mechanism of pyranose 2‐oxidase and other related enzymes in the glucose–methanol–choline superfamily
T Wongnate, P Chaiyen - The FEBS Journal, 2013 - Wiley Online Library
Enzymes in the glucose–methanol–choline (GMC) oxidoreductase superfamily catalyze the
oxidation of an alcohol moiety to the corresponding aldehyde. In this review, the current …
oxidation of an alcohol moiety to the corresponding aldehyde. In this review, the current …
A survey of genes encoding H2O2-producing GMC oxidoreductases in 10 Polyporales genomes
The genomes of three representative Polyporales (Bjerkandera adusta, Phlebia brevispora
and a member of the Ganoderma lucidum complex) recently were sequenced to expand our …
and a member of the Ganoderma lucidum complex) recently were sequenced to expand our …
Proton-coupled electron transfer and adduct configuration are important for C4a-hydroperoxyflavin formation and stabilization in a flavoenzyme
T Wongnate, P Surawatanawong… - Journal of the …, 2014 - ACS Publications
Determination of the mechanism of dioxygen activation by flavoenzymes remains one of the
most challenging problems in flavoenzymology for which the underlying theoretical basis is …
most challenging problems in flavoenzymology for which the underlying theoretical basis is …
Stabilization of C4a-hydroperoxyflavin in a two-component flavin-dependent monooxygenase is achieved through interactions at flavin N5 and C4a atoms
K Thotsaporn, P Chenprakhon, J Sucharitakul… - Journal of Biological …, 2011 - ASBMB
p-Hydroxyphenylacetate (HPA) 3-hydroxylase is a two-component flavin-dependent
monooxygenase. Based on the crystal structure of the oxygenase component (C 2), His-396 …
monooxygenase. Based on the crystal structure of the oxygenase component (C 2), His-396 …
One‐Pot Bioconversion of l‐Arabinose to l‐Ribulose in an Enzymatic Cascade
L Chuaboon, T Wongnate, P Punthong… - Angewandte Chemie …, 2019 - Wiley Online Library
This work reports the one‐pot enzymatic cascade that completely converts l‐arabinose to l‐
ribulose using four reactions catalyzed by pyranose 2‐oxidase (P2O), xylose reductase …
ribulose using four reactions catalyzed by pyranose 2‐oxidase (P2O), xylose reductase …
The 1.6 Å Crystal Structure of Pyranose Dehydrogenase from Agaricus meleagris Rationalizes Substrate Specificity and Reveals a Flavin Intermediate
TC Tan, O Spadiut, T Wongnate, J Sucharitakul… - PLoS …, 2013 - journals.plos.org
Pyranose dehydrogenases (PDHs) are extracellular flavin-dependent oxidoreductases
secreted by litter-decomposing fungi with a role in natural recycling of plant matter. All major …
secreted by litter-decomposing fungi with a role in natural recycling of plant matter. All major …