The limitations of central nervous system (CNS) drug delivery conferred by the blood-brain
barrier (BBB) have been a significant obstacle in the development of large molecule …

Background Owing to the rising costs of health care delivery, the quality of delivered care
has become a central issue across all medical specialties. Consequently, there is increasing …

OBJECTIVE The aim of this study was to provide a comprehensive benchmark of 30-day
ventriculoperitoneal (VP) shunt failure rates for a single institution over a 5-year study period …

Background Ventriculoperitoneal shunts are prone to common complications such as
infection or mechanical failure, but more insidious events can easily be missed. Distal shunt …

OBJECTIVE Many studies have aimed to determine the most clinically effective surgical
intervention for hydrocephalus. However, the costs associated with each treatment option …

Objective Ventriculoperitoneal (VP) shunt complication is a major obstacle in the
management of hydrocephalus. To study the differences of VP shunt complications between …

Object Cerebrospinal fluid shunts are the mainstay of the treatment of hydrocephalus. In past
studies, outcomes of shunt surgery have been analyzed based on follow-up of 1 year or …

Methods: All CPs performed between 2012 and 2019 were analyzed under IRB protocol
approval. Surgeries were categorized as either primary (no previous CP; n= 279) or revision …

The diagnosis of brain metastases is associated with a poor prognosis reflecting
uncontrolled primary disease that has spread to the relative sanctuary of the central nervous …

Background We showed that ventriculoperitoneal (VP) shunt and lumboperitoneal (LP)
shunt surgeries are beneficial for patients with idiopathic normal pressure hydrocephalus …