NLRP3 inflammasome in hepatic diseases: A pharmacological target

E Ramos-Tovar, P Muriel - Biochemical Pharmacology, 2023 - Elsevier
The NOD-like receptor family pyrin domain containing 3 (NLRP3) inflammasome pathway is
mainly responsible for the activation and release of a cascade of proinflammatory mediators …

[HTML][HTML] SARS-CoV-2 and chronic hepatitis B: Focusing on the possible consequences of co-infection

S Shoraka, SR Mohebbi, SM Hosseini… - Journal of Clinical …, 2023 - Elsevier
The pandemic of 2019 coronavirus disease (COVID-19) has become a world public health
challenge. A new member of Coronaviridae family, named severe acute respiratory …

SOD1 inhibition enhances sorafenib efficacy in HBV‐related hepatocellular carcinoma by modulating PI3K/Akt/mTOR pathway and ROS‐mediated cell death

J Lee, J Kim, R Lee, E Lee, HI An… - Journal of Cellular …, 2024 - Wiley Online Library
Abstract Hepatitis B Virus (HBV) infection significantly elevates the risk of hepatocellular
carcinoma (HCC), with the HBV X protein (HBx) playing a crucial role in cancer progression …

[HTML][HTML] Dysregulation in the microbiota by HBV and HCV infection induces an altered cytokine profile in the pathobiome of infection

MDM Padilha, FT de Vasconcelos Melo… - The Brazilian Journal of …, 2025 - Elsevier
Viral hepatitis is a public health problem, about 1 million people die due to complications of
this viral disease, the etiological agents responsible for inducing cirrhosis and cellular …

Understanding lactate in the development of Hepatitis B virus-related hepatocellular carcinoma

SB Sheikhrobat, S Mahmoudvand… - Infectious Agents and …, 2024 - Springer
Abstract Hepatitis B Virus (HBV) is a hepatotropic virus that can establish a persistent and
chronic infection in humans. Chronic hepatitis B (CHB) infection is associated with an …

The Influence of ESR2 Gene Polymorphisms on Susceptibility to Hepatitis B Virus-Related Chronic Hepatitis, Liver Cirrhosis, and Hepatocellular Carcinoma

Z Jie, J Hongkun, Y Shi, Y Fengxun, L Xin, M Yijun… - Biochemical …, 2024 - Springer
Hepatocellular carcinoma (HCC) represents an estrogen-dependent tumor. The action of
estrogen is regulated via estrogen receptor (ER). Polymorphisms in ERα gene, ESR1, are …

The roles and mechanisms of miRNA in HBV-HCC carcinogenesis: Why no therapeutic agents after 30 years?

K Sartorius, B Sartorius, C Winkler, A Chuturgoon… - …, 2024 - search.ebscohost.com
Hepatitis B-associated hepatocellular carcinoma (HBV-HCC) remains an intractable high-
mortality solid tumor cancer that accounted for 42% of global HCC cases in 2019. Despite …

Hepatocarcinoma in HBV infection is controlled by the use of entecavir, interferon and tenofovir: viral suppression and restoration of hepatic decompensation

MDM Padilha, FT de Vasconcelos Melo… - Revista Eletrônica …, 2024 - acervomais.com.br
Objetivo: Elucidar como as terapias com interferons e análogos de nucleotídeos em
pacientes infectados pelo vírus da hepatite B ocasionam a reversão de cirrose hepática e …

[PDF][PDF] 소라페닙과DDC (Sodium diethyldithiocarbamate) 조합요법으로PI3K/Akt/mTOR 경로억제를통한B 형간염유래간암세포에서세포자멸사를유도함에대한연구

권용재 - 2024 - oak.ulsan.ac.kr
목적: 본 연구는 디설피람 유도체인 DDC (sodium diethyldithiocarbamate) 를 소라페닙과
조합하여 B 형간염 유래 간암세포에서의 항암 작용 가능성을 확인하고자 하였다. 대상 및 방법 …