The co‐occurring use and misuse of cannabis and tobacco: a review
A Agrawal, AJ Budney, MT Lynskey - Addiction, 2012 - Wiley Online Library
Aims Cannabis and tobacco use and misuse frequently co‐occur. This review examines the
epidemiological evidence supporting the life‐time co‐occurrence of cannabis and tobacco …
epidemiological evidence supporting the life‐time co‐occurrence of cannabis and tobacco …
A review of co‐morbid tobacco and cannabis use disorders: Possible mechanisms to explain high rates of co‐use
Background Tobacco and cannabis are among the most commonly used psychoactive
substances worldwide, and are often used in combination. Evidence suggests that tobacco …
substances worldwide, and are often used in combination. Evidence suggests that tobacco …
[HTML][HTML] Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use
Tobacco and alcohol use are leading causes of mortality that influence risk for many
complex diseases and disorders. They are heritable, and etiologically related, behaviors that …
complex diseases and disorders. They are heritable, and etiologically related, behaviors that …
Redefining phenotypes to advance psychiatric genetics: Implications from hierarchical taxonomy of psychopathology.
Genetic discovery in psychiatry and clinical psychology is hindered by suboptimal
phenotypic definitions. We argue that the hierarchical, dimensional, and data-driven …
phenotypic definitions. We argue that the hierarchical, dimensional, and data-driven …
Exome chip meta-analysis fine maps causal variants and elucidates the genetic architecture of rare coding variants in smoking and alcohol use
Background Smoking and alcohol use have been associated with common genetic variants
in multiple loci. Rare variants within these loci hold promise in the identification of biological …
in multiple loci. Rare variants within these loci hold promise in the identification of biological …
A genome-wide association study of behavioral disinhibition
We report results from a genome wide association study (GWAS) of five quantitative
indicators of behavioral disinhibition: nicotine, alcohol consumption, alcohol dependence …
indicators of behavioral disinhibition: nicotine, alcohol consumption, alcohol dependence …
Attention-deficit/hyperactivity disorder subtypes and substance use and use disorders in NESARC
D De Alwis, MT Lynskey, AM Reiersen, A Agrawal - Addictive behaviors, 2014 - Elsevier
Background Attention-deficit/hyperactivity disorder (ADHD) is associated with substance use
and substance use disorders (SUD). However, relatively little is known about the …
and substance use disorders (SUD). However, relatively little is known about the …
Three mutually informative ways to understand the genetic relationships among behavioral disinhibition, alcohol use, drug use, nicotine use/dependence, and their co …
Behavioral disinhibition is a trait hypothesized to represent a general vulnerability to the
development of substance use disorders. We used a large community-representative …
development of substance use disorders. We used a large community-representative …
Genetic and environmental influences on the familial transmission of externalizing disorders in adoptive and twin offspring
Importance Twin-family studies have shown that parent-child resemblance on substance
use disorders and antisocial behavior can be accounted for by the transmission of a general …
use disorders and antisocial behavior can be accounted for by the transmission of a general …
The difference between trait disinhibition and impulsivity—and why it matters for clinical psychological science.
In the psychological science field, there is substantial interest in quantifying individual
differences in self-regulatory capacity because of its transdiagnostic relevance to various …
differences in self-regulatory capacity because of its transdiagnostic relevance to various …