The increasing interest for Galleria mellonella larvae as an infection model is evidenced by
the number of papers reporting its use, which increases exponentially since the early 2010s …

There has been significant progress made in the field of nanopore biosensor development
and sequencing applications, which address previous limitations that restricted widespread …

Shotgun metatranscriptomics (MTX) is an increasingly practical way to survey microbial
community gene function and regulation at scale. This review begins by summarizing the …

RNA ligases are present across all forms of life. While enzymatic RNA ligation between 5′-
PO4 and 3′-OH termini is prevalent in viruses, fungi, and plants, such RNA ligases are yet …

In early January 2020, the novel coronavirus (SARS-CoV-2) responsible for a pneumonia
outbreak in Wuhan, China, was identified using next-generation sequencing (NGS) and …

Highly selective gene expression is a key requirement for antigenic variation in several
pathogens, allowing evasion of host immune responses and maintenance of persistent …

Pathogen genome sequencing has become a routine part of our response to active
outbreaks of infectious disease and should be an important part of our preparations for …

RNA modifications are important regulators of gene expression. In Trypanosoma brucei,
transcription is polycistronic and thus most regulation happens post-transcriptionally. N 6 …

Substitution of the queuine nucleobase precursor preQ1 by an azide-containing derivative
(azido-propyl-preQ1) led to incorporation of this clickable chemical entity into tRNA via …

Viruses are evolving at an alarming rate, spreading and inconspicuously adapting to cutting-
edge therapies. Therefore, the search for rapid, informative and reliable diagnostic methods …