Galleria mellonella as a Suitable Model of Bacterial Infection: Past, Present and Future
G Ménard, A Rouillon, V Cattoir… - Frontiers in cellular and …, 2021 - frontiersin.org
The increasing interest for Galleria mellonella larvae as an infection model is evidenced by
the number of papers reporting its use, which increases exponentially since the early 2010s …
the number of papers reporting its use, which increases exponentially since the early 2010s …
An introduction to nanopore sequencing: past, present, and future considerations
M MacKenzie, C Argyropoulos - Micromachines, 2023 - mdpi.com
There has been significant progress made in the field of nanopore biosensor development
and sequencing applications, which address previous limitations that restricted widespread …
and sequencing applications, which address previous limitations that restricted widespread …
Metatranscriptomics for the human microbiome and microbial community functional profiling
Shotgun metatranscriptomics (MTX) is an increasingly practical way to survey microbial
community gene function and regulation at scale. This review begins by summarizing the …
community gene function and regulation at scale. This review begins by summarizing the …
Chemoproteomic discovery of a human RNA ligase
Y Yuan, FM Stumpf, LA Schlor, OP Schmidt… - Nature …, 2023 - nature.com
RNA ligases are present across all forms of life. While enzymatic RNA ligation between 5′-
PO4 and 3′-OH termini is prevalent in viruses, fungi, and plants, such RNA ligases are yet …
PO4 and 3′-OH termini is prevalent in viruses, fungi, and plants, such RNA ligases are yet …
Bioinformatics resources for SARS-CoV-2 discovery and surveillance
T Hu, J Li, H Zhou, C Li, EC Holmes… - Briefings in …, 2021 - academic.oup.com
In early January 2020, the novel coronavirus (SARS-CoV-2) responsible for a pneumonia
outbreak in Wuhan, China, was identified using next-generation sequencing (NGS) and …
outbreak in Wuhan, China, was identified using next-generation sequencing (NGS) and …
Spatial integration of transcription and splicing in a dedicated compartment sustains monogenic antigen expression in African trypanosomes
Highly selective gene expression is a key requirement for antigenic variation in several
pathogens, allowing evasion of host immune responses and maintenance of persistent …
pathogens, allowing evasion of host immune responses and maintenance of persistent …
[HTML][HTML] Towards a post-pandemic future for global pathogen genome sequencing
Pathogen genome sequencing has become a routine part of our response to active
outbreaks of infectious disease and should be an important part of our preparations for …
outbreaks of infectious disease and should be an important part of our preparations for …
N6-methyladenosine in poly(A) tails stabilize VSG transcripts
IJ Viegas, JP de Macedo, L Serra, M De Niz… - Nature, 2022 - nature.com
RNA modifications are important regulators of gene expression. In Trypanosoma brucei,
transcription is polycistronic and thus most regulation happens post-transcriptionally. N 6 …
transcription is polycistronic and thus most regulation happens post-transcriptionally. N 6 …
Functional integration of a semi-synthetic azido-queuosine derivative into translation and a tRNA modification circuit
L Bessler, N Kaur, LM Vogt, L Flemmich… - Nucleic acids …, 2022 - academic.oup.com
Substitution of the queuine nucleobase precursor preQ1 by an azide-containing derivative
(azido-propyl-preQ1) led to incorporation of this clickable chemical entity into tRNA via …
(azido-propyl-preQ1) led to incorporation of this clickable chemical entity into tRNA via …
Current trends in diagnostics of viral infections of unknown etiology
Viruses are evolving at an alarming rate, spreading and inconspicuously adapting to cutting-
edge therapies. Therefore, the search for rapid, informative and reliable diagnostic methods …
edge therapies. Therefore, the search for rapid, informative and reliable diagnostic methods …