Centrioles are conserved microtubule-based organelles that form the core of the centrosome
and act as templates for the formation of cilia and flagella. Centrioles have important roles in …

The centriole is an ancient microtubule-based organelle with a conserved nine-fold
symmetry. Centrioles form the core of centrosomes, which organize the interphase …

Electron microscopy played a key role in establishing cell biology as a discipline, by
producing fundamental insights into cellular organization and ultrastructure. Many seminal …

The axoneme is the main extracellular part of cilia and flagella in eukaryotes. It consists of a
microtubule cytoskeleton, which normally comprises nine doublets. In motile cilia, dynein …

The centrosome was discovered in the late 19th century when mitosis was first described.
Long recognized as a key organelle of the spindle pole, its core component, the centriole …

Summary Polo-like kinase 4 (Plk4) is a key regulator of centriole duplication, but the
mechanism underlying its recruitment to mammalian centrioles is not understood. In flies …

Cryo-electron tomography provides low-resolution 3D views of cells, organelles, or viruses.
Macromolecular complexes present in multiple copies can be subsequently identified within …

Centrosomes are the main microtubule-organizing centre of animal cells and are important
for many critical cellular and developmental processes from cell polarization to cell division …

Centrioles are microtubule-based core components of centrosomes and cilia. They are
duplicated exactly once during S-phase progression. Central to formation of each new …

Centrioles are among the largest protein-based structures found in most cell types,
measuring approximately 250 nm in diameter and approximately 500 nm long in vertebrate …