The morbidity and mortality of HIV type-1 (HIV-1)-related diseases were dramatically
diminished by the grounds of the introduction of potent antiretroviral therapy, which induces …

Even though the thymus is exquisitely sensitive to acute insults like infection, shock, or
common cancer therapies such as cytoreductive chemo-or radiation-therapy, it also has a …

T cell recognition of unknown antigens relies on the tremendous diversity of the T cell
receptor (TCR) repertoire; generation of which can only occur in the thymus. TCR repertoire …

Highly active antiretroviral therapy (ART) can effectively inhibit virus replication and restore
immune function in most people living with human immunodeficiency virus (HIV). However …

Porcine reproductive and respiratory syndrome virus (PRRSV) dramatically affects the
thymus and its ability to carry out its normal functions. In particular, infection incapacitates …

Combination antiretroviral therapy has demonstrated proved effectiveness in suppressing
viral replication and significantly recovering CD4+ T cell count in HIV type-1 (HIV-1)-infected …

The association between gut microbiota and immunologic nonresponse among people
living with HIV (PLHIV) on antiretroviral therapy (ART) is not well documented. This study …

Latent HIV-1 persists indefinitely during antiretroviral therapy (ART) as an integrated silent
genome in long-lived memory CD4+ T cells. In untreated infections, immune activation …

The interaction between human immunodeficiency virus (HIV) and hematopoietic
stem/progenitor cells (HSPCs) has been of great interest. However, it remains unclear …

Despite more than three decades of studies and advances in combination antiretroviral
therapy (cART) against human immunodeficiency virus (HIV), the mechanisms that precisely …