Monkeypox: a review of epidemiological modelling studies and how modelling has led to mechanistic insight

M Banuet-Martinez, Y Yang, B Jafari, A Kaur… - Epidemiology & …, 2023 - cambridge.org
Human monkeypox (mpox) virus is a viral zoonosis that belongs to the Orthopoxvirus genus
of the Poxviridae family, which presents with similar symptoms as those seen in human …

Clinical and Preclinical Methods of Heat-Stabilization of Human Vaccines

GL Williamson, EM Bachelder… - Molecular …, 2024 - ACS Publications
Vaccines have historically faced challenges regarding stability, especially in regions lacking
a robust cold chain infrastructure. This review delves into established and emergent …

[HTML][HTML] Immunogenicity of COVID-19 vaccines and their effect on HIV reservoir in older people with HIV

VA Matveev, EZ Mihelic, E Benko, P Budylowski… - Iscience, 2023 - cell.com
Older individuals and people with HIV (PWH) were prioritized for COVID-19 vaccination, yet
comprehensive studies of the immunogenicity of these vaccines and their effects on HIV …

A phase 3 randomized controlled trial of a COVID-19 recombinant vaccine S-268019-b versus ChAdOx1 nCoV-19 in Japanese adults

S Iwata, AJ Pollard, Y Tada, S Omoto, RY Shibata… - Scientific Reports, 2024 - nature.com
Abstract We assessed S-268019-b, a recombinant spike protein vaccine with a squalene-
based adjuvant, for superiority in its immunogenicity over ChAdOx1 nCoV-19 vaccine …

Modeling the kinetics of the neutralizing antibody response against SARS-CoV-2 variants after several administrations of Bnt162b2

Q Clairon, M Prague, D Planas, T Bruel… - PLoS Computational …, 2023 - journals.plos.org
Because SARS-CoV-2 constantly mutates to escape from the immune response, there is a
reduction of neutralizing capacity of antibodies initially targeting the historical strain against …

Antibody response elicited by the SARS‐CoV‐2 vaccine booster in patients with multiple sclerosis: Who gains from it?

I Schiavetti, M Inglese, J Frau… - European Journal of …, 2023 - Wiley Online Library
Background and purpose Although two doses of COVID‐19 vaccine elicited a protective
humoral response in most persons with multiple sclerosis (pwMS), a significant group of …

Multiple cohort study of hospitalized SARS-CoV-2 in-host infection dynamics: Parameter estimates, identifiability, sensitivity and the eclipse phase profile

CS Korosec, MI Betti, DW Dick, HK Ooi… - Journal of Theoretical …, 2023 - Elsevier
Abstract Within-host SARS-CoV-2 modelling studies have been published throughout the
COVID-19 pandemic. These studies contain highly variable numbers of individuals and …

Determination of significant immunological timescales from mRNA-LNP-based vaccines in humans

IR Moyles, CS Korosec, JM Heffernan - Journal of Mathematical Biology, 2023 - Springer
A compartment model for an in-host liquid nanoparticle delivered mRNA vaccine is
presented. Through non-dimensionalisation, five timescales are identified that dictate the …

Association between vaccination status and severe health consequences among community-dwelling COVID-19 patients during Omicron BA. 1/BA. 2 and BA. 5 …

K Tomioka, K Uno, M Yamada - Environmental Health and …, 2023 - jstage.jst.go.jp
Background: Many previous studies have reported that COVID-19 vaccine effectiveness
decreased over time and declined with newly emerging variants. However, there are few …

Within-host evolution of SARS-CoV-2: how often are de novo mutations transmitted from symptomatic infections?

CS Korosec, LM Wahl, JM Heffernan - Virus Evolution, 2024 - academic.oup.com
Despite a relatively low mutation rate, the large number of severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) infections has allowed for substantial genetic …