Myocardial infarction is the most common form of acute coronary syndrome. Blockage of a
coronary artery due to blood clotting leads to ischemia and subsequent cell death in the form …

Garcinia mangostana L.(Clusiaceae) is a tropical tree native to Southeast Asia known as
mangosteen which fruits possess a distinctive and pleasant taste that has granted them the …

The NRF2–KEAP1 system is a fundamental component of the cellular response that controls
a great variety of transcriptional targets that are mainly involved in the regulation of redox …

Cerebral ischemia-reperfusion is a complicated pathological process. The injury and
cascade reactions caused by cerebral ischemia and reperfusion are characterized by high …

Multiple in vitro tests are widely applied to assess the anticancer activity of new compounds,
including their combinations and interactions with other drugs. The MTT (3-(4, 5 …

Cancer cells are characterized by genetic and epigenetic alterations and phytochemicals,
epigenetic modulators, are considered as promising candidates for epigenetic therapy of …

In numerous experimental models, sulforaphane (SFN) is shown herein to induce hormetic
dose responses that are not only common but display endpoints of biomedical and clinical …

Epigallocatechin gallate (EGCG) is the most abundant and effective green tea catechin and
has been reported to attenuate diabetic nephropathy (DN). However, the mechanism by …

Prediabetes and diabetes are rising worldwide. Control of blood glucose is crucial to prevent
or delay diabetic complications that frequently result in increased morbidity and mortality …

Chromium (Cr) is an internationally recognized carcinogenic hazard that causes serious
pulmonary toxicity. However, Cr-induced pulmonary toxicity lacks effective treatment to date …