The analysis of molecular mechanisms of disease progression challenges the development
of bioinformatics tools and omics data integration. We have presented an earlier series of …

Molecular heterogeneity in prostate cancer (PCa) is one of the key reasons underlying the
differing likelihoods of recurrence after surgical treatment in individual patients of the same …

Background Osteosarcoma (OS) is the most common primary malignant bone neoplasm.
Growing researches have highlighted the tumor promoting role of miR-615-3p in various …

Background Occludin (OCLN) is an important tight junction protein and has been reported to
be abnormally expressed in the development of malignant tumors. However, its biomarker …

Background The tumor microenvironment (TME) in lung adenocarcinoma (LUAD) influences
tumor progression and immunosuppressive phenotypes through cell communication. We …

MicroRNAs (miRNAs) are a class of small non-coding RNAs that may function as tumor
suppressors or oncogenes. Alteration of their expression levels has been linked to a range …

Background The research of cancer treatments has always been a hot topic in medical field.
Cancer monotherapy as a common therapy has been proven to have many disadvantages …