Mammalian sperm cells must respond to cues originating from along the female
reproductive tract and from the layers of the egg in order to complete their fertilization …

Abstract The 3′, 5′-cyclic adenosine monophosphate (cAMP) dependent protein kinase
(PKA) is a tetrameric holoenzyme comprising a set of two regulatory subunits (PKA-R) and …

Technical design features for improving the way a passive elastic filament produces
propulsive thrust can be understood by analyzing the deformation of sperm‐templated …

To fertilize an oocyte, the membrane potential of both mouse and human sperm must
hyperpolarize (become more negative inside). Determining the molecular mechanisms …

Na+/H+ exchangers (NHEs) are a family of ion transporters that regulate the pH of various
cell compartments across an array of cell types. In eukaryotes, NHEs are encoded by the …

Infertility affects 10 to 15% of couples worldwide, with a male factor contributing up to 50% of
these cases. The primary tool for diagnosing male infertility is traditional semen analysis …

Progesterone and prostaglandin E1 are postulated to trigger the human sperm acrosome
reaction (AR). However, their reported efficacy is very variable which likely, in part, reflects …

Prediction of a boar's fertility level has great economic importance for sow herds. After
standard sperm morphology and motility metrics are met, approximately 25% of boars have …

Na+/H+ exchangers (NHEs) are known to be important regulators of pH in multiple
intracellular compartments of eukaryotic cells. Sperm function is especially dependent on …

The standard model of the cell membrane potential Vm describes it as arising from diffusion
currents across a membrane with a constant electric field, with zero electric field outside the …