Preparation of peptide and protein powders for inhalation

KA Johnson - Advanced drug delivery reviews, 1997 - Elsevier
Innovations in biotechnology and recombinant techniques have led to a large increase in
the number of macromolecule drugs developed over the last several years. These …

Protein formulation

J Andya, JL Cleland, CC Hsu, XM Lam… - US Patent …, 2001 - Google Patents
(57) ABSTRACT A stable lyophilized protein formulation is described which can be
reconstituted with a Suitable diluent to generate a high protein concentration reconstituted …

Automatic biological analyte testing meter with integrated lancing device and methods of use

CR Saikley, PR Hamerton-Kelly, S Sia… - US Patent …, 2009 - Google Patents
An integrated device is for sampling and testing an analyte. The device generally includes a
housing, a lancing device for sampling an analyte, a test strip for substantially capturing at …

Thermophysical properties of trehalose and its concentrated aqueous solutions

DP Miller, JJ de Pablo, H Corti - Pharmaceutical research, 1997 - Springer
Purpose. To address the lack of fundamental thermophysical data for trehalose and its
aqueous systems by measuring equilibrium and non-equilibrium properties of such systems …

Protein formulation

J Andya, JL Cleland, CC Hsu, XM Lam… - US Patent …, 2004 - Google Patents
4,714,759 A 12/1987 Whitaker, Jr. can be reconstituted with a Suitable diluent to generate a
high 4,753,894 A 6/1988 Frankel et al. protein concentration reconstituted formulation which …

Disposable injector device

BJ Roser - US Patent 6,102,896, 2000 - Google Patents
The present invention is a single use injector device for injecting parenteral medications
which operates by hand force. The injector device has a plunger section and a base. As …

Capping bioprosthetic tissue to reduce calcification

J Dove, D Dobler, J Davidson, GA Wright - US Patent 8,357,387, 2013 - Google Patents
US8357387B2 - Capping bioprosthetic tissue to reduce calcification - Google Patents
US8357387B2 - Capping bioprosthetic tissue to reduce calcification - Google Patents Capping …

Spray drying of macromolecules to produce inhaleable dry powders

RM Platz, JS Patton, L Foster, M Eljamal - US Patent 6,582,728, 2003 - Google Patents
3,764,716 A 10/1973 Rainwater et al.(57) ABSTRACT 3,921,637 A 11/1975 Bennie et al.
3,964,483 A 6/1976 Mathes According to the subject invention, dispersible dry poWder …

Formulation of a reconstituted protein, and method and kit for the production thereof

SJ Prestrelski, MZ Zhang - US Patent 5,580,856, 1996 - Google Patents
Dried proteins are stabilized against loss of biological activ ity in formulations by adding an
reconstitution stabilizer upon rehydration of the dried protein. A kit for producing and a …

Methods and compositions for pulmonary delivery of insulin

JS Patton, L Foster, RM Platz - US Patent 5,997,848, 1999 - Google Patents
US5997848A - Methods and compositions for pulmonary delivery of insulin - Google Patents
US5997848A - Methods and compositions for pulmonary delivery of insulin - Google Patents …