Acute respiratory distress syndrome: causes, pathophysiology, and phenotypes
LDJ Bos, LB Ware - The Lancet, 2022 - thelancet.com
Acute respiratory distress syndrome (ARDS) is a common clinical syndrome of acute
respiratory failure as a result of diffuse lung inflammation and oedema. ARDS can be …
respiratory failure as a result of diffuse lung inflammation and oedema. ARDS can be …
Acute respiratory distress syndrome in adults: diagnosis, outcomes, long-term sequelae, and management
EA Gorman, CM O'Kane, DF McAuley - The Lancet, 2022 - thelancet.com
Acute respiratory distress syndrome (ARDS) is characterised by acute hypoxaemic
respiratory failure with bilateral infiltrates on chest imaging, which is not fully explained by …
respiratory failure with bilateral infiltrates on chest imaging, which is not fully explained by …
Endothelial dysfunction triggers acute respiratory distress syndrome in patients with sepsis: a narrative review
Acute respiratory distress syndrome (ARDS) is a severe organ failure occurring mainly in
critically ill patients as a result of different types of insults such as sepsis, trauma or …
critically ill patients as a result of different types of insults such as sepsis, trauma or …
Advancing precision medicine for the diagnosis and treatment of acute respiratory distress syndrome
AN Rizzo, NR Aggarwal, BT Thompson… - Journal of Clinical …, 2023 - mdpi.com
Acute respiratory distress syndrome (ARDS) is a common and life-threatening cause of
respiratory failure. Despite decades of research, there are no effective pharmacologic …
respiratory failure. Despite decades of research, there are no effective pharmacologic …
Application of anti-inflammatory treatment in two different ovine acute respiratory distress syndrome injury models: a preclinical randomized intervention study
K Wildi, S Livingstone, C Ainola, SM Colombo… - Scientific Reports, 2023 - nature.com
Whilst the presence of 2 subphenotypes among the heterogenous Acute Respiratory
Distress Syndrome (ARDS) population is becoming clinically accepted, subphenotype …
Distress Syndrome (ARDS) population is becoming clinically accepted, subphenotype …
Receptor for advanced glycation end-products promotes activation of alveolar macrophages through the NLRP3 Inflammasome/TXNIP axis in acute lung injury
W Lenga Ma Bonda, M Fournet, R Zhai, J Lutz… - International Journal of …, 2022 - mdpi.com
The roles of thioredoxin-interacting protein (TXNIP) and receptor for advanced glycation end-
products (RAGE)-dependent mechanisms of NOD-like receptor family, pyrin domain …
products (RAGE)-dependent mechanisms of NOD-like receptor family, pyrin domain …
A Focused Review of the Initial Management of Patients with Acute Respiratory Distress Syndrome
A Motes, T Singh, N Vinan Vega, K Nugent - Journal of Clinical Medicine, 2023 - mdpi.com
At present, the management of patients with acute respiratory distress syndrome (ARDS)
largely focuses on ventilator settings to limit intrathoracic pressures by using low tidal …
largely focuses on ventilator settings to limit intrathoracic pressures by using low tidal …
Effects of sevoflurane on lung epithelial permeability in experimental models of acute respiratory distress syndrome
R Zhai, W Lenga Ma Bonda, C Leclaire… - Journal of Translational …, 2023 - Springer
Background Preclinical studies in acute respiratory distress syndrome (ARDS) have
suggested that inhaled sevoflurane may have lung-protective effects and clinical trials are …
suggested that inhaled sevoflurane may have lung-protective effects and clinical trials are …
Biological markers to predict outcome in mechanically ventilated patients with severe COVID-19 living at high altitude
Background: There is not much evidence on the prognostic utility of different biological
markers in patients with severe COVID-19 living at high altitude. The objective of this study …
markers in patients with severe COVID-19 living at high altitude. The objective of this study …
[HTML][HTML] Traits, trends and hits of orphan drug designations in cystic fibrosis
E Costa, S Girotti, HA van den Ham, M Cipolli… - Journal of Cystic …, 2023 - Elsevier
Abstract Background In the United States (US) and in Europe, cystic fibrosis (CF) qualifies as
a rare disease, thus positioning the field to benefit from regulatory incentives provided by …
a rare disease, thus positioning the field to benefit from regulatory incentives provided by …