Palmitoylethanolamide (PEA, N-hexadecanoylethanolamide) is an endogenous compound
belonging to the family of N-acylethanolamines. PEA has anti-inflammatory and analgesic …

Growing evidence supports the pivotal role played by oxidative stress in tissue injury
development, thus resulting in several pathologies including cardiovascular, renal …

Background Metabolomics is a novel tool to explore the biological mechanisms of the health
effects of fine particulate matter (PM 2.5) air pollution. Very few studies have examined the …

Chronic inflammation and oxidative stress, features that are closely associated with nuclear
factor (NF-κB) activation, play a key role in the development and progression of chronic …

Neurotoxicity is a main side effect of the anticancer drug oxaliplatin. The development of a
neuropathic syndrome impairs quality of life and potentially results in chemotherapy dose …

We investigated the influence of cannabidiol (CBD) on blood pressure (BP) and heart rate
(HR) in spontaneously (SHR) and deoxycorticosterone (DOCA-salt) hypertensive rats …

Peroxisome proliferator–activated receptor-α (PPARα) regulates hepatic fatty acid
catabolism and mediates the metabolic response to starvation. Recently we found that …

Background Experimental studies provide evidence for antidepressant effects of
Palmitoylethanolamide (PEA) in animal models of depression. We aimed to evaluate the …

Virtually every cellular process is affected by diet and this represents the foundation of
dietary management to a variety of small animal disorders. Special attention is currently …

In this work, we investigated the effects of red orange and lemon extract (RLE) on ochratoxin
A (OTA)‐induced nephrotoxicity. In particular, we analyzed the change in renal function and …