Neutrophils in cancer: heterogeneous and multifaceted

CC Hedrick, I Malanchi - Nature Reviews Immunology, 2022 - nature.com
Neutrophils are the most abundant myeloid cells in human blood and are emerging as
important regulators of cancer. However, their functional importance has often been …

NETworking with cancer: The bidirectional interplay between cancer and neutrophil extracellular traps

JM Adrover, SAC McDowell, XY He, DF Quail… - Cancer Cell, 2023 - cell.com
Neutrophils are major effectors and regulators of the immune system. They play critical roles
not only in the eradication of pathogens but also in cancer initiation and progression …

Somatic mutation landscapes at single-molecule resolution

F Abascal, LMR Harvey, E Mitchell, ARJ Lawson… - Nature, 2021 - nature.com
Somatic mutations drive the development of cancer and may contribute to ageing and other
diseases,. Despite their importance, the difficulty of detecting mutations that are only present …

[HTML][HTML] Tumor-associated neutrophils and neutrophil-targeted cancer therapies

H Que, Q Fu, T Lan, X Tian, X Wei - … et Biophysica Acta (BBA)-Reviews on …, 2022 - Elsevier
Neutrophils are the frontline cells in response to microbial infections and are involved in a
range of inflammatory disorders in the body. In recent years, neutrophils have gained …

[HTML][HTML] Co-option of neutrophil fates by tissue environments

I Ballesteros, A Rubio-Ponce, M Genua, E Lusito… - Cell, 2020 - cell.com
Classically considered short-lived and purely defensive leukocytes, neutrophils are unique
in their fast and moldable response to stimulation. This plastic behavior may underlie …

Effects of omega-3 fatty acids on immune cells

S Gutiérrez, SL Svahn, ME Johansson - International journal of molecular …, 2019 - mdpi.com
Alterations on the immune system caused by omega-3 fatty acids have been described for
30 years. This family of polyunsaturated fatty acids exerts major alterations on the activation …

The neutrophil's role during health and disease

PX Liew, P Kubes - Physiological reviews, 2019 - journals.physiology.org
Neutrophils have always been considered as uncomplicated front-line troopers of the innate
immune system equipped with limited proinflammatory duties. Yet recently, the role of the …

The local microenvironment drives activation of neutrophils in human brain tumors

RR Maas, K Soukup, N Fournier, M Massara, S Galland… - Cell, 2023 - cell.com
Neutrophils are abundant immune cells in the circulation and frequently infiltrate tumors in
substantial numbers. However, their precise functions in different cancer types remain …

[HTML][HTML] Neutrophil: a cell with many roles in inflammation or several cell types?

C Rosales - Frontiers in physiology, 2018 - frontiersin.org
Neutrophils are the most abundant leukocytes in the circulation, and have been regarded as
first line of defense in the innate arm of the immune system. They capture and destroy …

Mechanisms of ADC toxicity and strategies to increase ADC tolerability

TD Nguyen, BM Bordeau, JP Balthasar - Cancers, 2023 - mdpi.com
Simple Summary Antibody-drug conjugates (ADC) are a rapidly expanding class of anti-
cancer drugs, with twelve agents in current clinical use. Despite recent successes, many …