In the young of many mammalian species, including humans, a vigorous and highly
rewarding social activity is abundantly expressed, known as social play behaviour. Social …

Highlights•Adolescence may be a period of heightened sensitivity to social reward.•Playing
with a conspecific is more rewarding for adolescent than adult rats.•Human adolescents …

Social interaction is a complex behavior essential for many species and is impaired in major
neuropsychiatric disorders. Pharmacological studies have implicated certain …

Emotional stress is considered a severe pathogenetic factor of psychiatric disorders.
However, the circuit mechanisms remain largely unclear. Using a three-chamber vicarious …

Adolescence is a developmental period in which the mesolimbic dopaminergic “reward”
circuitry of the brain, including the nucleus accumbens (NAc), undergoes significant …

The adolescent transition is associated with increases in reward-and sensation-seeking,
peer-directed social interactions, and risk-taking, with exploratory use of alcohol and other …

Adolescence is characterized by heightened reward sensitivity. Accumulating evidence
suggests that this behavior is associated with neurodevelopmental changes in reward …

Background A large proportion of adolescents drink alcohol, with many engaging in high-
risk patterns of consumption, including binge drinking. Here, we systematically review and …

Rationale Research on adolescence and drug abuse increased substantially in the past
decade. However, drug-addiction-related behaviors following stressful experiences during …

Social play behavior is the most vigorous and characteristic form of social interaction
displayed by developing mammals. The laboratory rat is an ideal species to study this …