Coordinated efforts of different actin filament populations are needed for optimal cell wound repair

J Hui, M Nakamura, J Dubrulle… - Molecular biology of the …, 2023 - Am Soc Cell Biol
Cells are subjected to a barrage of daily insults that often lead to their cortices being ripped
open and requiring immediate repair. An important component of the cell's repair response …

Scar/WAVE has Rac GTPase-independent functions during cell wound repair

M Nakamura, J Hui, V Stjepić, SM Parkhurst - Scientific Reports, 2023 - nature.com
Rho family GTPases regulate both linear and branched actin dynamics by activating
downstream effectors to facilitate the assembly and function of complex cellular structures …

WAVE2 Regulates Actin-Dependent Processes Induced by the B Cell Antigen Receptor and Integrins

A Bedi, K Choi, C Keane, M Bolger-Munro… - Cells, 2023 - mdpi.com
B cell antigen receptor (BCR) signaling induces actin cytoskeleton remodeling by
stimulating actin severing, actin polymerization, and the nucleation of branched actin …

[HTML][HTML] The WAVE complex forms linear arrays at negative membrane curvature to instruct lamellipodia formation

M Wu, P Marchando, K Meyer, Z Tang, DN Woolfson… - …, 2024 - pmc.ncbi.nlm.nih.gov
Cells generate a wide range of actin-based membrane protrusions for various cell
behaviors. These protrusions are organized by different actin nucleation promoting factors …

Identifying proteins that preferentially bind ATP-over ADP-F-actin

S Claydon - 2024 - theses.gla.ac.uk
The cytoskeleton is a dynamic network of proteins that grants cells internal organisation,
structure and mobility. This gives cells the ability to participate in all manner of physiological …