▪ Abstract The energy landscape theory of protein folding is a statistical description of a
protein's potential surface. It assumes that folding occurs through organizing an ensemble of …

General principles of protein structure, stability, and folding kinetics have recently been
explored in computer simulations of simple exact lattice models. These models represent …

Lattice protein folding models are a cornerstone of computational biophysics. Although
these models are a coarse grained representation, they provide useful insight into the …

A theory of helix formation in collapsed polymers relates the measured amount of helix in the
collapsed states to the conformational entropy associated with different chain topologies …

Publisher Summary This chapter describes the present state of the studies of the molten
globule state and its role in protein folding and physiological processes. Recent data on the …

A general formalism to compute configurational properties of proteins and other
heteropolymers with an arbitrary sequence of charges and non-uniform excluded volume …

Background Halophilic prokaryotes are adapted to thrive in extreme conditions of salinity.
Identification and analysis of distinct macromolecular characteristics of halophiles provide …

As was noted in our recent review, 1 the protein folding field underwent a cyclic
development. Initially, protein folding was viewed as a strictly experimental field belonging to …

In stark contrast to foldable proteins with a unique folded state, intrinsically disordered
proteins and regions (IDPs) persist in perpetually disordered ensembles. Yet an IDP …

There have been considerable attempts in the past to relate phenotypic trait—habitat
temperature of organisms—to their genotypes, most importantly compositions of their …