Synthesis of 1,3,5-Triazepines and Benzo[f][1,3,5]triazepines and Their Biological Activity: Recent Advances and New Approaches

AA Abu-Hashem, O Hakami, N Amri, YE Mukhrish… - Molecules, 2024 - mdpi.com
This review article discusses the recent progress in synthesizing seven-membered ring 1, 3,
5-triazepine and benzo [f][1, 3, 5] triazepine derivatives. These derivatives can be either …

Synthesis, anticancer activity and molecular docking of new quinolines, quinazolines and 1, 2, 4-triazoles with pyrido [2, 3-d] pyrimidines

AA Abu-Hashem, O Hakami, N Amri - Heliyon, 2024 - cell.com
Recently, heterocyclic compounds such as pyrido [2, 3-d] pyrimidinones, 1, 2, 4-
triazolopyrimidines, pyrimidoquinazolines, and quinoline derivatives have gained attention …

[HTML][HTML] Design, Synthesis, Antimicrobial Activity, and Molecular Docking of Novel Thiazoles, Pyrazoles, 1, 3-Thiazepinones, and 1, 2, 4-Triazolopyrimidines Derived …

AA Abu-Hashem, SA Al-Hussain - Pharmaceuticals, 2024 - mdpi.com
Background: Recently, pyrido [2, 3-d] pyrimidine, triazolopyrimidine, thiazolopyrimidine,
quinoline, and pyrazole derivatives have gained attention due to their diverse biological …

[HTML][HTML] Design, synthesis, and structure–activity relationship of 2-chloro-3-formylquinoline containing hybrids as powerful antibacterial agents

HM Abumelha, AM Alqahtani, H Alharbi… - Journal of Saudi …, 2024 - Elsevier
This work aims to evaluate the antimicrobial activity of some new quinoline derivatives
linked to pyrazole derivatives. The target compounds pyrazolylvinylquinoline 11a-g and 12a …

[HTML][HTML] One-pot sustainable synthesis of novel pyrido [2, 3-d] pyrimidinones and their evaluation for antitubercular and anticancer activity

S Tabassum, SG Ramaraj, J Rajprasad… - Journal of …, 2025 - Elsevier
A novel green protocol for the construction of diversified pyrido [2, 3-d] pyrimidinones was
accomplished by a single-pot reaction of aryl aldehydes, Meldrum's acid, thiobarbituric acid …

Synthesis, characterization and antimicrobial activity of V (IV) complexes containing 2, 6-pyridinedicarboxylate (DPA) ligand

ZA Alkaya, J Abdusalamov, H İlkimen… - Journal of Molecular …, 2024 - Elsevier
A novel molecular coordination compound,[V 4 IV O 4 (DPA) 4 (OH 2) 4]∙ 2H 2 O, 1, and
known [V IV O (DPA)(OH 2) 2]. 2H 2 O compound, 2, were obtained from V 2 O 5 and 2, 6 …

Bio Inspired CdO Nanoparticles: A Robust and Recyclable Catalyst Towards the Synthesis of Dihydropyrimidone Derivatives via One Pot Three‐Component …

PS Bera, J Mahato, R Das, P Mondal… - …, 2024 - Wiley Online Library
An innovative and environmentally sustainable approach is presented for the synthesis of
cadmium oxide nanoparticles (CdONPs), leveraging the leaf extract of the pigeon pea plant …

Indole–thiazolidinedione–triazole hybrids: synthesis, molecular docking, absorption, distribution, metabolism and excretion (ADME) profiling, and biological evaluation …

MP Dholariya, AS Patel - Chemistry Letters, 2024 - academic.oup.com
A novel series of hybrid indole–thiazolidinedione–triazole derivatives (6a-l) were
synthesized and assessed for their in vitro inhibitory activity against porcine pancreatic α …

New Tetrazole-Annulated Pyrazolyl–Pyrimidine Derivatives as Antimycobacterial Targets: Design, Synthesis, Molecular Docking, and ADME Profiling

A Basireddy, S Basireddy, T Allaka, M Afzal… - Russian Journal of …, 2024 - Springer
Herein, the constructing synthon pyrazolyl-pyrimidine derivatives were synthesized and
utilized for building a wide variety of 1, 2, 3-triazole and tetrazole compounds that can be …

Design, Synthesis and Anticancer Activity of New Quinolines, Quinazolines and 1, 2, 4-Triazoles with Pyrido [2, 3-d] Pyrimidines

AA Abu-Hashem, O Hakami, N Amri - Quinazolines and - papers.ssrn.com
Design, Synthesis and Anticancer Activity of New Quinolines, Quinazolines and 1,2,4-Triazoles
with Pyrido[2,3-d] Pyrimidines by Ameen Ali Abu-Hashem, Othman Hakami, Nasser Amri …