Bacterial type III secretion systems: specialized nanomachines for protein delivery into target cells

JE Galán, M Lara-Tejero, TC Marlovits… - Annual review of …, 2014 - annualreviews.org
One of the most exciting developments in the field of bacterial pathogenesis in recent years
is the discovery that many pathogens utilize complex nanomachines to deliver bacterially …

Bacterial type III secretion systems: a complex device for the delivery of bacterial effector proteins into eukaryotic host cells

S Wagner, I Grin, S Malmsheimer… - FEMS microbiology …, 2018 - academic.oup.com
Virulence-associated type III secretion systems (T3SS) serve the injection of bacterial
effector proteins into eukaryotic host cells. They are able to secrete a great diversity of …

Protein export according to schedule: architecture, assembly, and regulation of type III secretion systems from plant-and animal-pathogenic bacteria

D Büttner - Microbiology and Molecular Biology Reviews, 2012 - Am Soc Microbiol
Flagellar and translocation-associated type III secretion (T3S) systems are present in most
Gram-negative plant-and animal-pathogenic bacteria and are often essential for bacterial …

Molecular Pathogenesis of Shigella spp.: Controlling Host Cell Signaling, Invasion, and Death by Type III Secretion

GN Schroeder, H Hilbi - Clinical microbiology reviews, 2008 - Am Soc Microbiol
Shigella spp. are gram-negative pathogenic bacteria that evolved from harmless
enterobacterial relatives and may cause devastating diarrhea upon ingestion. Research …

[HTML][HTML] 类鼻疽伯克霍尔德菌感染与免疫逃逸机制的研究进展

李倩, 毛旭虎 - 2020 - jmi.fudan.edu.cn
类鼻疽是由类鼻疽伯克霍尔德菌(Burkholderia pseudomallei, B. pseudomallei)(简称类鼻疽菌)
感染引起的一种热带医学疾病. 该病临床表现复杂多样, 严重感染时可快速发展为败血症 …

Molecular Insights into Burkholderia pseudomallei and Burkholderia mallei Pathogenesis

EE Galyov, PJ Brett, D DeShazer - Annual review of …, 2010 - annualreviews.org
Burkholderia pseudomallei and Burkholderia mallei are closely related gram-negative
bacteria that can cause serious diseases in humans and animals. This review summarizes …

Bacterial contact-dependent delivery systems

CS Hayes, SK Aoki, DA Low - Annual review of genetics, 2010 - annualreviews.org
Bacteria have developed remarkable systems that sense neighboring target cells upon
contact and initiate a series of events that enhance their survival and growth at the expense …

Assembly of the bacterial type III secretion machinery

A Diepold, S Wagner - FEMS microbiology reviews, 2014 - academic.oup.com
Many bacteria that live in contact with eukaryotic hosts, whether as symbionts or as
pathogens, have evolved mechanisms that manipulate host cell behaviour to their benefit …

[HTML][HTML] Assembly and structure of the T3SS

BJ Burkinshaw, NCJ Strynadka - … et Biophysica Acta (BBA)-Molecular Cell …, 2014 - Elsevier
Abstract The Type III Secretion System (T3SS) is a multi-mega Dalton apparatus assembled
from more than twenty components and is found in many species of animal and plant …

The type III secretion system tip complex and translocon

CA Mueller, P Broz, GR Cornelis - Molecular microbiology, 2008 - Wiley Online Library
The type III secretion machinery of Gram‐negative bacteria, also known as the injectisome
or needle complex, is composed of a basal body spanning both bacterial membranes and …