Odorant receptors and odorant-binding proteins as insect pest control targets: a comparative analysis

H Venthur, JJ Zhou - Frontiers in physiology, 2018 - frontiersin.org
Recently, two alternative targets in insect periphery nerve system have been explored for
environmentally-friendly approaches in insect pest management, namely odorant-binding …

Reception of odors and repellents in mosquitoes

A Ray - Current opinion in neurobiology, 2015 - Elsevier
Highlights•Mosquitoes sense exhaled CO 2 and skin odor to find humans.•Attractive
odorants can be used as lures in mosquito traps.•Inhibitors of the mosquito CO 2 receptor …

New Halogenated Compounds from Halimeda macroloba Seaweed with Potential Inhibitory Activity against Malaria

AH Elmaidomy, EM Zahran, R Soltane, A Alasiri… - Molecules, 2022 - mdpi.com
Malaria is one of the most important infectious diseases worldwide. The causative of the
most severe forms of malaria, Plasmodium falciparum, has developed resistances against …

Metabolic activity organizes olfactory representations

WW Qian, JN Wei, B Sanchez-Lengeling, BK Lee… - Elife, 2023 - elifesciences.org
Hearing and vision sensory systems are tuned to the natural statistics of acoustic and
electromagnetic energy on earth and are evolved to be sensitive in ethologically relevant …

Current and potential biotechnological applications of odorant-binding proteins

NF Brito, DS Oliveira, TC Santos, MF Moreira… - Applied microbiology …, 2020 - Springer
Odorant-binding proteins (OBPs) are small soluble proteins whose biological function is
believed to be facilitating olfaction by assisting the transport of volatile chemicals in both …

Repellent screening of selected plant essential oils against dengue fever mosquitoes using behavior bioassays

W Deng, M Li, S Liu, JG Logan, J Mo - Neotropical Entomology, 2023 - Springer
Among the efforts to reduce mosquito-transmitted diseases, such as malaria and dengue
fever, essential oils (EOs) have become increasingly popular as natural replacements for the …

The crystal structure of the AgamOBP1• Icaridin complex reveals alternative binding modes and stereo-selective repellent recognition

CE Drakou, KE Tsitsanou, C Potamitis… - Cellular and Molecular …, 2017 - Springer
Abstract Anopheles gambiae Odorant Binding Protein 1 in complex with the most widely
used insect repellent DEET, was the first reported crystal structure of an olfactory …

Efficacy of nanogels containing carvacrol, cinnamaldehyde, thymol, and a mix compared to a standard repellent against Anopheles stephensi

A Sanei-Dehkordi, S Hatami, E Zarenezhad… - Industrial Crops and …, 2022 - Elsevier
Mosquito-borne diseases are responsible for about one million death annually worldwide.
Especially in endemic regions, using repellents is a practical approach to preventing such …

Identification of novel bioinspired synthetic mosquito repellents by combined ligand-based screening and OBP-structure-based molecular docking

T Thireou, G Kythreoti, KE Tsitsanou, K Koussis… - Insect biochemistry and …, 2018 - Elsevier
In this work we report a fast and efficient virtual screening protocol for discovery of novel
bioinspired synthetic mosquito repellents with lower volatility and, in all likelihood, increased …

Evaluation of the Activity of the Essential Oil from an Ornamental Flower against Aedes aegypti: Electrophysiology, Molecular Dynamics and Behavioral Assays

PC Bezerra-Silva, KA Dutra, GKN Santos, RCS Silva… - PloS one, 2016 - journals.plos.org
Dengue fever has spread worldwide and affects millions of people every year in tropical and
subtropical regions of Africa, Asia, Europe and America. Since there is no effective vaccine …