Haemonchosis in Sheep and Goats, Control Strategies and Development of Vaccines against Haemonchus contortus

I Adduci, F Sajovitz, B Hinney, K Lichtmannsperger… - Animals, 2022 - mdpi.com
Simple Summary Haemonchus contortus is the most pathogenic blood-feeding parasitic
nematode in sheep and goats, threatening animal welfare and causing tremendous …

Immunity to Haemonchus contortus and vaccine development

AJ Nisbet, EN Meeusen, JF González… - Advances in …, 2016 - Elsevier
Sheep are capable of developing protective immunity to Haemonchus contortus through
repeated exposure to this parasite, although this immune protection is the result of a …

Comprehensive analysis of the secreted proteins of the parasite Haemonchus contortus reveals extensive sequence variation and differential immune recognition

AP Yatsuda, J Krijgsveld, AWCA Cornelissen… - Journal of Biological …, 2003 - ASBMB
Haemonchus contortus is a nematode that infects small ruminants. It releases a variety of
molecules, designated excretory/secretory products (ESP), into the host. Although the …

Developments and hurdles in generating vaccines for controlling helminth parasites of grazing ruminants

WD Smith, DS Zarlenga - Veterinary parasitology, 2006 - Elsevier
As a direct consequence of rising drug resistance among common nematodes of grazing
animals, efforts toward state-of-the-art vaccine development have clearly intensified in …

Progress in the development of subunit vaccines for gastrointestinal nematodes of ruminants

JB Matthews, P Geldhof, T Tzelos… - Parasite …, 2016 - Wiley Online Library
The global increase in anthelmintic resistant nematodes of ruminants, together with
consumer concerns about chemicals in food, necessitates the development of alternative …

Progress and new technologies for developing vaccines against gastrointestinal nematode parasites of sheep

SE Newton, ENT Meeusen - Parasite immunology, 2003 - Wiley Online Library
Despite the identification of highly effective native antigens for vaccination against
Haemonchus contortus, particularly 'hidden'antigens derived from the intestine of adult …

High throughput LC-MS/MS-based proteomic analysis of excretory-secretory products from short-term in vitro culture of Haemonchus contortus

T Wang, G Ma, CS Ang, PK Korhonen, AV Koehler… - Journal of …, 2019 - Elsevier
Parasitic nematodes of humans, animals and plants have a major, adverse impact on global
health and agricultural production worldwide. To cope with their surrounding environment in …

Toxoplasma gondii Isolates of Free-Ranging Chickens From Rio de Janeiro, Brazil: Mouse Mortality, Genotype, and Oocyst Shedding by Cats

JP Dubey, DH Graham, DS da Silva… - Journal of …, 2003 - meridian.allenpress.com
Most isolates of Toxoplasma gondii can be grouped into 3 genetic lineages. In the present
study, 67 isolates of T. gondii were obtained by bioassay in mice inoculated with brains and …

Inhibition of Haemonchus contortus larval development by fungal lectins

C Heim, H Hertzberg, A Butschi, S Bleuler-Martinez… - Parasites & vectors, 2015 - Springer
Background Lectins are carbohydrate-binding proteins that are involved in fundamental intra-
and extracellular biological processes. They occur ubiquitously in nature and are especially …

Vaccination against Ostertagia ostertagi with subfractions of the protective ES-thiol fraction

Y Meyvis, P Geldhof, K Gevaert, E Timmerman… - Veterinary …, 2007 - Elsevier
Previous vaccination trials against Ostertagia ostertagi in cattle have demonstrated the
protective capacity of a protein fraction termed ES-thiol, which is enriched for activation …