[HTML][HTML] Symposium review: The genomic architecture of inbreeding: How homozygosity affects health and performance

CF Baes, BO Makanjuola, F Miglior, G Marras… - Journal of dairy …, 2019 - Elsevier
Inbreeding depression is a growing concern in livestock because it can detrimentally affect
animal fitness, health, and production levels. Genomic information can be used to more …

A review of selected genes with known effects on performance and health of cattle

E Casas, ME Kehrli Jr - Frontiers in veterinary science, 2016 - frontiersin.org
There are genetic conditions that influence production in dairy and beef cattle. The objective
of this review was to describe relevant genetic conditions that have been associated with …

[HTML][HTML] Phenotypic and genetic effects of recessive haplotypes on yield, longevity, and fertility

JB Cole, DJ Null, PM VanRaden - Journal of dairy science, 2016 - Elsevier
Phenotypes from the August 2015 US national genetic evaluation were used to compute
phenotypic effects of 18 recessive haplotypes in Ayrshire (n= 1), Brown Swiss (n= 5) …

The Holstein Friesian Lethal Haplotype 5 (HH5) Results from a Complete Deletion of TBF1M and Cholesterol Deficiency (CDH) from an ERV-(LTR) Insertion into the Coding …

E Schütz, C Wehrhahn, M Wanjek, R Bortfeld… - PloS one, 2016 - journals.plos.org
Background With the availability of massive SNP data for several economically important
cattle breeds, haplotype tests have been performed to identify unknown recessive disorders …

A transposable element insertion in APOB causes cholesterol deficiency in Holstein cattle

F Menzi, N Besuchet‐Schmutz, M Fragnière… - Animal …, 2016 - Wiley Online Library
Cholesterol deficiency, a new autosomal recessive inherited genetic defect in Holstein
cattle, has been recently reported to have an influence on the rearing success of calves. The …

Гаплотипы фертильности голштинского скота

НА Зиновьева - Сельскохозяйственная биология, 2016 - cyberleninka.ru
Голштинскую породу крупного рогатого скота разводят по крайней мере в 161 стране,
на долю животных голштинской и голштинизированной черно-пестрой пород в общем …

A missense mutation in TUBD1 is associated with high juvenile mortality in Braunvieh and Fleckvieh cattle

H Schwarzenbacher, J Burgstaller, FR Seefried… - BMC genomics, 2016 - Springer
Background Haplotypes with reduced or missing homozygosity may harbor deleterious
alleles that compromise juvenile survival. A scan for homozygous haplotype deficiency …

GWAS reveals determinants of mobilization rate and dynamics of an active endogenous retrovirus of cattle

L Tang, B Swedlund, S Dupont, C Harland… - Nature …, 2024 - nature.com
Five to ten percent of mammalian genomes is occupied by multiple clades of endogenous
retroviruses (ERVs), that may count thousands of members. New ERV clades arise by …

[HTML][HTML] Selected Monogenic Genetic Diseases in Holstein Cattle—A Review

M Gozdek, S Mucha, A Prostek, T Sadkowski - Genes, 2024 - mdpi.com
Genetic disorders arise from alterations in the hereditary information encoded in DNA,
leading to potential detrimental effects on the well-being and vitality of organisms. Within the …

[HTML][HTML] Development and application of KASP assays for rapid screening of 8 genetic defects in Holstein cattle

Y Zhang, D Liang, H Huang, Z Yang, Y Wang… - Journal of Dairy …, 2020 - Elsevier
Specific DNA mutations underlying several genetic defects associated with embryo loss or
reduced calf survivability have been identified in dairy cattle, and a convenient and cost …