Macro-/micro-environment-sensitive chemosensing and biological imaging

Z Yang, J Cao, Y He, JH Yang, T Kim, X Peng… - Chemical Society …, 2014 - pubs.rsc.org
Environment-related parameters, including viscosity, polarity, temperature, hypoxia, and pH,
play pivotal roles in controlling the physical or chemical behaviors of local molecules. In …

Fluorescent chemosensors based on spiroring-opening of xanthenes and related derivatives

X Chen, T Pradhan, F Wang, JS Kim, J Yoon - Chemical reviews, 2012 - ACS Publications
The recognition and sensing of biologically and environmentally important species has
emerged as a significant goal in the field of chemical sensors in recent years. 1Ā10 Several …

Fluorescent indicators for intracellular pH

J Han, K Burgess - Chemical reviews, 2010 - ACS Publications
Intracellular pH (pHi) 1, 2 plays many critical roles in cell, enzyme, and tissue activities,
including proliferation and apoptosis, 3–8 multidrug resistance (MDR), 9 ion transport, 10 …

A near-infrared neutral pH fluorescent probe for monitoring minor pH changes: imaging in living HepG2 and HL-7702 cells

B Tang, F Yu, P Li, L Tong, X Duan, T Xie… - Journal of the …, 2009 - ACS Publications
A near-neutral pH near-infrared (NIR) fluorescent probe utilizing a fluorophore-spacer-
receptor molecular framework that can modulate the fluorescence emission intensity through …

Hemicyanine-based high resolution ratiometric near-infrared fluorescent probe for monitoring pH changes in vivo

Y Li, Y Wang, S Yang, Y Zhao, L Yuan… - Analytical …, 2015 - ACS Publications
Intracellular pH is an important parameter associated with cellular behaviors and
pathological conditions. Quantitative sensing pH and monitoring its changes by near …

Dual-emitting fluorescent metal–organic framework nanocomposites as a broad-range pH sensor for fluorescence imaging

H Chen, J Wang, D Shan, J Chen, S Zhang… - Analytical …, 2018 - ACS Publications
pH plays an important role in understanding physiological/pathologic processes, and
abnormal pH is a symbol of many common diseases such as cancer, stroke, and Alzheimer's …

A novel acidotropic pH indicator and its potential application in labeling acidic organelles of live cells

Z Diwu, CS Chen, C Zhang, DH Klaubert… - Chemistry & biology, 1999 - cell.com
Background Ratio imaging has received intensive attention in the past few decades. The
growing potential of ratio imaging is significantly limited, however, by the lack of appropriate …

Ratiometric emission fluorescent pH probe for imaging of living cells in extreme acidity

W Niu, L Fan, M Nan, Z Li, D Lu, MS Wong… - Analytical …, 2015 - ACS Publications
A novel ratiometric emission fluorescent probe, 1, 1-dimethyl-2-[2-(quinolin-4-yl) vinyl]-1 H-
benzo [e] indole (QVBI), is facilely synthesized via ethylene bridging of benzoindole and …

Ratiometric fluorescence nanoprobes for subcellular pH imaging with a single-wavelength excitation in living cells

W Pan, H Wang, L Yang, Z Yu, N Li, B Tang - Analytical chemistry, 2016 - ACS Publications
Abnormal pH values in the organelles are closely associated with inappropriate cellular
functions and many diseases. Monitoring subcellular pH values and their variations is …

A highly sensitive acidic pH fluorescent probe and its application to HepG2 cells

W Zhang, B Tang, X Liu, Y Liu, K Xu, J Ma, L Tong… - Analyst, 2009 - pubs.rsc.org
A novel acidic fluorescent probe 1 has been designed, synthesized, characterized and
evaluated in vivo as optical imaging of intracellular H+. The design strategy for the probe is …