Neuroendocrine neoplasms (NENs) are a group of heterogeneous tumors with
neuroendocrine differentiation that can arise from any organ. They account for 2% of all …

Somatostatin (SST) is a small peptide that exerts inhibitory effects on a wide range of
neuroendocrine cells. Due to the fact that somatostatin regulates cell growth and hormone …

We describe the development of OncoFAP, an ultra-high-affinity ligand of fibroblast
activation protein (FAP) for targeting applications with pan-tumoral potential. OncoFAP binds …

Background CC‐90011 is an oral, potent, selective, reversible inhibitor of lysine‐specific
demethylase 1 (LSD1) that was well tolerated, with encouraging activity in patients who had …

Simple Summary Neuroendocrine refers to the cells that synthesize and secrete messenger
chemicals such as neuropeptides and amines. Neuroendocrine neoplasms (NENs) are …

Neuroendocrine neoplasms (NENs) are a heterogeneous group of neoplasms ranging from
well-differentiated, slowly growing tumors to poorly differentiated carcinomas. These tumors …

Dysregulation of the splicing machinery is emerging as a hallmark in cancer due to its
association with multiple dysfunctions in tumor cells. Inappropriate function of this machinery …

Thirty-seven patients with advanced gastroenteropancreatic neuroendocrine tumors
(GEPNETs) were treated on a prospective phase II single-center study with four cycles of 7.8 …

Neuroendocrine neoplasms (NENs) comprise a highly heterogeneous group of tumors
arising from the diffuse neuroendocrine system. NENs mainly originate in gastrointestinal …

Endogenous somatostatin shows anti-secretory effects in both physiological and
pathological settings, as well as inhibitory activity on cell growth. Since somatostatin is not …