[HTML][HTML] Alzheimer's disease as a viral disease: Revisiting the infectious hypothesis
Alzheimer's disease (AD) represents the most frequent type of dementia in elderly people.
Two major forms of the disease exist: sporadic-the causes of which have not yet been fully …
Two major forms of the disease exist: sporadic-the causes of which have not yet been fully …
Drug repurposing for viral infectious diseases: how far are we?
B Mercorelli, G Palù, A Loregian - Trends in microbiology, 2018 - cell.com
Despite the recent advances in controlling some viral pathogens, most viral infections still
lack specific treatment. Indeed, the need for effective therapeutic strategies to combat 'old' …
lack specific treatment. Indeed, the need for effective therapeutic strategies to combat 'old' …
Host calcium channels and pumps in viral infections
X Chen, R Cao, W Zhong - Cells, 2019 - mdpi.com
Ca2+ is essential for virus entry, viral gene replication, virion maturation, and release. The
alteration of host cells Ca2+ homeostasis is one of the strategies that viruses use to …
alteration of host cells Ca2+ homeostasis is one of the strategies that viruses use to …
Neurological involvements of SARS-CoV2 infection
COVID-19 is a pandemic viral infection caused by a novel coronavirus, SARS-CoV2, which
is a global concern of the twenty-first century for its rapid spreading in a short period. Apart …
is a global concern of the twenty-first century for its rapid spreading in a short period. Apart …
Advances in developing therapies to combat Zika virus: current knowledge and future perspectives
Zika virus (ZIKV) remained largely quiescent for nearly six decades after its first appearance
in 1947. ZIKV reappeared after 2007, resulting in a declaration of an international “public …
in 1947. ZIKV reappeared after 2007, resulting in a declaration of an international “public …
Antiviral agents in development for Zika virus infections
In 1947, Zika virus (ZIKV), a mosquito-borne flavivirus was identified in Uganda and
subsequently spread to Asia and the Pacific regions. In 2015, it was introduced in Brazil …
subsequently spread to Asia and the Pacific regions. In 2015, it was introduced in Brazil …
Ribosomal biogenesis as an emerging target of neurodevelopmental pathologies
M Hetman, LP Slomnicki - Journal of neurochemistry, 2019 - Wiley Online Library
Abstract Development of the nervous system is carried out by complex gene expression
programs that are regulated at both transcriptional and translational level. In addition, quality …
programs that are regulated at both transcriptional and translational level. In addition, quality …
The role of glial cells in Zika virus‐induced neurodegeneration
A Quincozes‐Santos, LD Bobermin, NLF Costa… - Glia, 2023 - Wiley Online Library
Zika virus (ZIKV) is a strongly neurotropic flavivirus whose infection has been associated
with microcephaly in neonates. However, clinical and experimental evidence indicate that …
with microcephaly in neonates. However, clinical and experimental evidence indicate that …
Neuroprotection by agmatine: Possible involvement of the gut microbiome?
P Saha, S Panda, A Holkar, R Vashishth… - Ageing Research …, 2023 - Elsevier
Agmatine, an endogenous polyamine derived from L-arginine, elicits tremendous
multimodal neuromodulant properties. Alterations in agmatinergic signalling are closely …
multimodal neuromodulant properties. Alterations in agmatinergic signalling are closely …
Therapeutic treatment of Zika virus infection using a brain-penetrating antiviral peptide
JA Jackman, VV Costa, S Park, ALCV Real, JH Park… - Nature Materials, 2018 - nature.com
Zika virus is a mosquito-borne virus that is associated with neurodegenerative diseases,
including Guillain–Barré syndrome and congenital Zika syndrome. As Zika virus targets the …
including Guillain–Barré syndrome and congenital Zika syndrome. As Zika virus targets the …