The development of blood-handling medical devices, such as ventricular assist devices,
requires the analysis of their biocompatibility. Among other aspects, this includes hemolysis …

Background: Hemolysis and its complications are major concerns during the clinical
application of blood pumps. In-vitro circulatory testing loops have been employed as the key …

Abstract Background The Food and Drug Administration (FDA) blood pump is an open‐
source benchmark cardiovascular device introduced for validating computational and …

Hemolysis is the most important issue to consider in the design and optimization of blood-
contacting devices. Although the use of Computational Fluid Dynamics (CFD) in hemolysis …

Background Veno-venous extracorporeal membrane oxygenation (VV ECMO) has become
standard of care in patients with the most severe forms of acute respiratory distress …

A blood turbine-pump system (iATVA), resembling a turbocharger was proposed as a
mechanical right-heart assist device without external drive power. In this study, the iATVA …

This study applies non-intrusive polynomial chaos expansion (NIPCE) surrogate modeling
to analyze the performance of a rotary blood pump (RBP) across its operating range. We …

Objective: Reynolds Averaged Navier Stokes (RANS) models are often used as the basis for
modeling blood damage in turbulent flows. To predict blood damage by turbulence stresses …

Purpose: The purpose of this study is to address the lack of uncertainty quantification in
numerical hemolysis models, which are critical for medical device evaluations. Specifically …

In recent decades, significant effort has been put into designing ventricular assist devices to
treat heart conditions, as heart transplantation can benefit only a small number of patients …