Comprehensive review of targeted therapy for colorectal cancer
YH Xie, YX Chen, JY Fang - Signal transduction and targeted therapy, 2020 - nature.com
Colorectal cancer (CRC) is among the most lethal and prevalent malignancies in the world
and was responsible for nearly 881,000 cancer-related deaths in 2018. Surgery and …
and was responsible for nearly 881,000 cancer-related deaths in 2018. Surgery and …
Overview of current targeted therapy in gallbladder cancer
X Song, Y Hu, Y Li, R Shao, F Liu, Y Liu - Signal Transduction and …, 2020 - nature.com
Gallbladder cancer (GBC) is rare, but is the most malignant type of biliary tract tumor.
Unfortunately, only a small population of cancer patients is acceptable for the surgical …
Unfortunately, only a small population of cancer patients is acceptable for the surgical …
[PDF][PDF] YTHDF3 induces the translation of m6A-enriched gene transcripts to promote breast cancer brain metastasis
Brain metastasis is a major cause of cancer mortality, but its molecular mechanisms are
severely understudied. In addition, little is known regarding the role of m 6 A reader YTHDF3 …
severely understudied. In addition, little is known regarding the role of m 6 A reader YTHDF3 …
Loss of XIST in breast cancer activates MSN-c-Met and reprograms microglia via exosomal miRNA to promote brain metastasis
Up to 30% of patients with metastatic breast cancer eventually develop brain metastasis, yet
the pathologic mechanism behind this development remains poorly understood. Here, we …
the pathologic mechanism behind this development remains poorly understood. Here, we …
[PDF][PDF] Metastasis organotropism: redefining the congenial soil
Metastasis is the most devastating stage of cancer progression and causes the majority of
cancer-related deaths. Clinical observations suggest that most cancers metastasize to …
cancer-related deaths. Clinical observations suggest that most cancers metastasize to …
Feed‐forward loops between metastatic cancer cells and their microenvironment—the stage of escalation
Z Baumann, P Auf der Maur… - EMBO Molecular …, 2022 - embopress.org
Breast cancer is the most frequent cancer among women, and metastases in distant organs
are the leading cause of the cancer‐related deaths. While survival of early‐stage breast …
are the leading cause of the cancer‐related deaths. While survival of early‐stage breast …
Type I interferon response in astrocytes promotes brain metastasis by enhancing monocytic myeloid cell recruitment
W Ma, MC Oliveira-Nunes, K Xu, A Kossenkov… - Nature …, 2023 - nature.com
Cancer metastasis to the brain is a significant clinical problem. Metastasis is the
consequence of favorable interactions between invaded cancer cells and the …
consequence of favorable interactions between invaded cancer cells and the …
Polyunsaturated fatty acids from astrocytes activate PPARγ signaling in cancer cells to promote brain metastasis
Y Zou, A Watters, N Cheng, CE Perry, K Xu, GM Alicea… - Cancer Discovery, 2019 - AACR
Brain metastasis, the most lethal form of melanoma and carcinoma, is the consequence of
favorable interactions between the invading cancer cells and the brain cells. Peroxisome …
favorable interactions between the invading cancer cells and the brain cells. Peroxisome …
Emerging trends in colorectal cancer: Dysregulated signaling pathways
R Ahmad, JK Singh, A Wunnava… - International …, 2021 - spandidos-publications.com
Colorectal cancer (CRC) is the third most frequently detected type of cancer, and the second
most common cause of cancer‑related mortality globally. The American Cancer Society …
most common cause of cancer‑related mortality globally. The American Cancer Society …
The evolving modern management of brain metastasis
The incidence of brain metastases is increasing as cancer therapies improve and patients
live longer, providing new challenges to the multidisciplinary teams that care for these …
live longer, providing new challenges to the multidisciplinary teams that care for these …