Lipid and carbohydrate metabolism are highly conserved processes that affect nearly all
aspects of organismal biology. Caenorhabditis elegans eat bacteria, which consist of lipids …

Chemosensory neurons translate perception of external chemical cues, including odorants,
tastants, and pheromones, into information that drives attraction or avoidance motor …

Many critical events in the Plasmodium life cycle rely on the controlled release of Ca2+ from
intracellular stores to activate stage-specific Ca2+-dependent protein kinases. Using the …

Fragile X–associated tremor/ataxia syndrome (FXTAS) is a late‐onset neurodegenerative
disorder that affects some but not all carriers of small, noncoding CGG‐repeat expansions …

Most eukaryotic cells express small regulatory RNAs. The purpose of one class, the somatic
endogenous siRNAs (endo-siRNAs), remains unclear. Here, we show that the endo-siRNA …

The nematode Caenorhabditis elegans is a powerful model organism to study functions of
polyunsaturated fatty acids. The ability to alter fatty acid composition with genetic …

Sensory experience modifies behavior through both associative and non-associative
learning. In Caenorhabditis elegans, pairing odor with food deprivation results in aversive …

Behavioral plasticity allows animals to modulate their behavior based on experience and
environmental conditions. Caenorhabditis elegans exhibits experience-dependent changes …

An exciting discovery of the new millennium is that primary cilia, organelles found on most
eukaryotic cells, play crucial roles in vertebrate development by modulating Hedgehog, Wnt …

Insulin/insulin-like growth factor (IGF) receptor signaling (IIS) supports context-dependent
learning in vertebrates and invertebrates. Here, we identify cell-specific mechanisms of IIS …