Molecular basis of restenosis and drug-eluting stents

MA Costa, DI Simon - Circulation, 2005 - Am Heart Assoc
Next is a granulation or cellular proliferation phase. Growth factors are subsequently
released from platelets, leukocytes, and SMCs, which stimulate migration of SMCs from the …

Coronary in-stent restenosis: current status and future strategies

HC Lowe, SN Oesterle, LM Khachigian - Journal of the American College of …, 2002 - jacc.org
In-stent restenosis (ISR) is a novel pathobiologic process, histologically distinct from
restenosis after balloon angioplasty and comprised largely of neointima formation. As …

In-stent restenosis: contributions of inflammatory responses and arterial injury to neointimal hyperplasia

R Kornowski, MK Hong, FO Tio, O Bramwell… - Journal of the American …, 1998 - jacc.org
Objectives. We examined the relative contributions of inflammation and arterial injury to
neointimal formation in a porcine coronary overstretch restenosis model. Background …

[图书][B] Handbook of membrane separations: chemical, pharmaceutical, food, and biotechnological applications

AK Pabby, SSH Rizvi, AMS Requena - 2008 - taylorfrancis.com
The Handbook of Membrane Separations: Chemical, Pharmaceutical, and Biotechnological
Applications provides detailed information on membrane separation technologies as they …

Hematopoietic stem cells differentiate into vascular cells that participate in the pathogenesis of atherosclerosis

M Sata, A Saiura, A Kunisato, A Tojo, S Okada… - Nature medicine, 2002 - nature.com
Excessive accumulation of smooth-muscle cells (SMCs) has a key role in the pathogenesis
of vascular diseases. It has been assumed that SMCs derived from the outer medial layer …

Acute and chronic tissue response to coronary stent implantation: pathologic findings in human specimen

PH Grewe, T Deneke, A Machraoui, J Barmeyer… - Journal of the American …, 2000 - jacc.org
OBJECTIVES The aim of our study was to analyze the cellular components of neointimal
tissue regeneration after coronary stenting. BACKGROUND High restenosis rates are a …

A mouse model of vascular injury that induces rapid onset of medial cell apoptosis followed by reproducible neointimal hyperplasia

M Sata, Y Maejima, F Adachi, K Fukino, A Saiura… - Journal of molecular and …, 2000 - Elsevier
Genetically modified mice serve as a powerful tool to determine the role of specific
molecules in a wide variety of biological phenomena including vascular remodeling. Several …

Vascular cell apoptosis in remodeling, restenosis, and plaque rupture

K Walsh, RC Smith, HS Kim - Circulation research, 2000 - Am Heart Assoc
Apoptotic death of vascular cells is a prominent feature of blood vessel remodeling that
occurs during normal development and fibroproliferative disorders of the vessel wall. This …

Favorable effect of VEGF gene transfer on ischemic peripheral neuropathy

P Schratzberger, G Schratzberger, M Silver, C Curry… - Nature medicine, 2000 - nature.com
Ischemic peripheral neuropathy is a frequent, irreversible complication of lower extremity
vascular insufficiency. We investigated whether ischemic peripheral neuropathy could be …

Highly increased cell proliferation activity in the restenotic hemodialysis vascular access after percutaneous transluminal angioplasty: implication in prevention of …

CJ Chang, PJ Ko, LA Hsu, YS Ko, YL Ko… - American Journal of …, 2004 - Elsevier
Background: The effect of percutaneous transluminal angioplasty (PTA) in the treatment of
hemodialysis vascular access stenosis is attenuated by a high restenosis rate, which results …