[HTML][HTML] Microfluidic platforms for cell cultures and investigations

ML Coluccio, G Perozziello, N Malara, E Parrotta… - Microelectronic …, 2019 - Elsevier
This review covers several aspects of microfluidic devices used for culturing and monitoring
of both adherent and non-adherent cells, including a multitude of applications. A comparison …

Cyclic olefin polymers: emerging materials for lab-on-a-chip applications

PS Nunes, PD Ohlsson, O Ordeig, JP Kutter - Microfluidics and …, 2010 - Springer
Cyclic olefin polymers (COPs) are increasingly popular as substrate material for
microfluidics. This is due to their promising properties, such as high chemical resistance, low …

Lab-on-a-Foil: microfluidics on thin and flexible films

M Focke, D Kosse, C Müller, H Reinecke, R Zengerle… - Lab on a Chip, 2010 - pubs.rsc.org
This critical review is motivated by an increasing interest of the microfluidics community in
developing complete Lab-on-a-Chip solutions based on thin and flexible films (Lab-on-a …

Reduction of surface roughness for optical quality microfluidic devices in PMMA and COC

IRG Ogilvie, VJ Sieben, CFA Floquet… - Journal of …, 2010 - iopscience.iop.org
A rapid and low-cost technique is presented for the fabrication of optical quality microfluidic
devices in poly (methyl methacrylate)(PMMA) or cyclic olefin copolymer (COC). When …

[HTML][HTML] Microdosing for drug delivery application—A review

AB Bußmann, LM Grünerbel, CP Durasiewicz… - Sensors and Actuators A …, 2021 - Elsevier
There is an increasing amount of research on microfluidic actuators with the aim to improve
drug dosing applications. Micropumps are promising as they reduce the size and energy …

Microstructuring of polymer films for sensitive genotyping by real-time PCR on a centrifugal microfluidic platform

M Focke, F Stumpf, B Faltin, P Reith, D Bamarni… - Lab on a Chip, 2010 - pubs.rsc.org
We present a novel process flow enabling prototyping of microfluidic cartridges made out of
polymer films. Its high performance is proven by implementation of a microfluidic genotyping …

UV-femtosecond-laser structuring of cyclic olefin copolymer

K Bischoff, D Mücke, GL Roth, C Esen, R Hellmann - Polymers, 2022 - mdpi.com
We report on the laser ablation of cyclic olefin copolymer using an amplified ultrashort
pulsed laser in the ultraviolet spectral range. In addition to a high ablation depth per laser …

Femtosecond laser direct generation of 3D-microfluidic channels inside bulk PMMA

GL Roth, C Esen, R Hellmann - Optics Express, 2017 - opg.optica.org
We report on laser direct generation of 3D-microchannels for microfluidic applications inside
PMMA bulk material by focused femtosecond pulses. Inner lying channels with cross …

Birefringence in injection-molded cyclic olefin copolymer substrates and its impact on integrated photonic structures

S Kefer, T Limbach, N Pape, K Klamt, B Schmauss… - Polymers, 2024 - mdpi.com
This contribution quantifies the birefringence within injection-molded cyclic olefin copolymer
plates and discusses its impact on the mechanical properties of the plates. It also focuses on …

Micromachining of PMMA—manufacturing of burr-free structures with single-edge ultra-small micro end mills

IG Reichenbach, M Bohley, FJP Sousa… - The International Journal …, 2018 - Springer
Nowadays, the prototypes of microfluidic systems are generally produced via micromilling of
thermoplastic polymethyl methacrylate (PMMA). The main limitations are the design of micro …