Classically, polyunsaturated fatty acids (PUFA) were largely thought to be relatively inert
structural components of brain, largely important for the formation of cellular membranes …

The brain is highly enriched with fatty acids. These include the polyunsaturated fatty acids
(PUFAs) arachidonic acid and docosahexaenoic acid, which are largely esterified to the …

Docosahexaenoic acid (DHA) is the most abundant n-3 polyunsaturated fatty acid in the
brain where it serves to regulate several important processes and, in addition, serves as a …

The life expectancy of the global population has increased. Aging is a natural physiological
process that poses major challenges in an increasingly long-lived and frail population …

Mitochondrial dysfunction represents a common early pathological event in brain aging and
in neurodegenerative diseases, eg, in Alzheimer's (AD), Parkinson's (PD), and Huntington's …

Docosahexaenoic acid (DHA, 22: 6n-3) is an omega-3 polyunsaturated fatty acid (PUFA)
essential for neural development, learning, and vision. Although DHA can be provided to …

Long-chain omega-3 fatty acids esterified in lysophosphatidylcholine (LPC-omega-3) are
the most bioavailable omega-3 fatty acid form and are considered important for brain health …

Although the human lifespan has increased in the past century owing to advances in
medicine and lifestyle, the human healthspan has not kept up the same pace, especially in …

Abstract Docosahexaenoic acid (DHA; 22: 6 ω-3) is highly enriched in the brain and is
required for proper brain development and function. Its deficiency has been shown to be …

Docosahexaenoic acid (DHA) is the main essential omega-3 fatty acid in brain tissues
required for normal brain development and function. An alteration of brain DHA in …