Molecular diversity of spider venom

AA Vassilevski, SA Kozlov, EV Grishin - Biochemistry (Moscow), 2009 - Springer
Spider venom, a factor that has played a decisive role in the evolution of one of the most
successful groups of living organisms, is reviewed. Unique molecular diversity of venom …

Recent advances in the understanding of brown spider venoms: From the biology of spiders to the molecular mechanisms of toxins

LH Gremski, D Trevisan-Silva, VP Ferrer… - Toxicon, 2014 - Elsevier
The Loxosceles genus spiders (the brown spiders) are encountered in all the continents,
and the clinical manifestations following spider bites include skin necrosis with gravitational …

Venomics: unravelling the complexity of animal venoms with mass spectrometry

P Escoubas, L Quinton… - Journal of mass …, 2008 - Wiley Online Library
Animal venoms and toxins are now recognized as major sources of bioactive molecules that
may be tomorrow's new drug leads. Their complexity and their potential as drug sources …

Ecological venomics: How genomics, transcriptomics and proteomics can shed new light on the ecology and evolution of venom

K Sunagar, D Morgenstern, AM Reitzel, Y Moran - Journal of Proteomics, 2016 - Elsevier
Animal venom is a complex cocktail of bioactive chemicals that traditionally drew interest
mostly from biochemists and pharmacologists. However, in recent years the evolutionary …

Biotechnological trends in spider and scorpion antivenom development

AH Laustsen, M Solà, EC Jappe, S Oscoz… - Toxins, 2016 - mdpi.com
Spiders and scorpions are notorious for their fearful dispositions and their ability to inject
venom into prey and predators, causing symptoms such as necrosis, paralysis, and …

Thrombin-like enzymes from snake venom: Structural characterization and mechanism of action

A Ullah, R Masood, I Ali, K Ullah, H Ali, H Akbar… - International journal of …, 2018 - Elsevier
Snake venom thrombin-like enzymes (SVTLEs) constitute the major portion (10–24%) of
snake venom and these are the second most abundant enzymes present in the crude …

Deadly proteomes: a practical guide to proteotranscriptomics of animal venoms

AA Walker, SD Robinson, BF Hamilton… - …, 2020 - Wiley Online Library
Animal venoms are renowned for their toxicity, biochemical complexity, and as a source of
compounds with potential applications in medicine, agriculture, and industry. Polypeptides …

Molecular evolution, functional variation, and proposed nomenclature of the gene family that includes sphingomyelinase D in sicariid spider venoms

GJ Binford, MR Bodner, MHJ Cordes… - Molecular biology …, 2009 - academic.oup.com
The venom enzyme sphingomyelinase D (SMase D) in the spider family Sicariidae (brown
or fiddleback spiders [Loxosceles] and six-eyed sand spiders [Sicarius]) causes …

Brown Spider (Loxosceles genus) Venom Toxins: Tools for Biological Purposes

OM Chaim, D Trevisan-Silva, D Chaves-Moreira… - Toxins, 2011 - mdpi.com
Venomous animals use their venoms as tools for defense or predation. These venoms are
complex mixtures, mainly enriched of proteic toxins or peptides with several, and different …

A novel expression profile of the Loxosceles intermedia spider venomous gland revealed by transcriptome analysis

LH Gremski, RB da Silveira, OM Chaim… - Molecular …, 2010 - pubs.rsc.org
Spiders of the Loxosceles genus are cosmopolitan, and their venom components possess
remarkable biological properties associated with their ability to act upon different molecules …