Implementation of regulatory standards has reduced exhaust emissions of particulate matter
from road traffic substantially in the developed world. However, nonexhaust particle …

Background and objective The question of whether children's exposure to traffic-related air
pollution (TRAP) contributes to their development of asthma is unresolved. We conducted a …

A complete understanding of how exposure to environmental substances promotes cancer
formation is lacking. More than 70 years ago, tumorigenesis was proposed to occur in a two …

The gut microbiome is associated with diverse diseases,–, but a universal signature of a
healthy or unhealthy microbiome has not been identified, and there is a need to understand …

Background Long-term exposure to ambient air pollution has been associated with
premature mortality, but associations at concentrations lower than current annual limit …

Rationale: Both genetic and environmental factors contribute to lung cancer, but the degree
to which air pollution modifies the impact of genetic susceptibility on lung cancer remains …

Abstract The Rotterdam Study is an ongoing prospective cohort study that started in 1990 in
the city of Rotterdam, The Netherlands. The study aims to unravel etiology, preclinical …

Various approaches have been proposed to model PM 2.5 in the recent decade, with
satellite-derived aerosol optical depth, land-use variables, chemical transport model …

BACKGROUND The growing scientific evidence for effects of air pollution on health at
concentrations below current air quality standards and the large burden of disease attributed …

Ambient air pollution increases the risk of respiratory mortality, but evidence for impacts on
lung function and chronic obstructive pulmonary disease (COPD) is less well established …