Polymicrobial wound infections: pathophysiology and current therapeutic approaches

S Bertesteanu, S Triaridis, M Stankovic, V Lazar… - International journal of …, 2014 - Elsevier
Acute and chronic wounds represent a very common health problem in the entire world. The
dermal wounds are colonized by aerobic and anaerobic bacterial and fungal strains, most of …

ZnO applications and challenges

O Oprea, E Andronescu, D Ficai, A Ficai… - Current Organic …, 2014 - ingentaconnect.com
Metal oxide nanoparticles represent a new class of important materials that are increasingly
being developed for use in research and health-related applications. Although the in vitro …

Modified wound dressing with phyto-nanostructured coating to prevent staphylococcal and pseudomonal biofilm development

I Anghel, AM Holban, AM Grumezescu… - Nanoscale research …, 2012 - Springer
This paper reports a newly fabricated nanophyto-modified wound dressing with microbicidal
and anti-adherence properties. Nanofluid-based magnetite doped with eugenol or limonene …

Silver based materials for biomedical applications

IA Nedelcu, A Ficai, M Sonmez, D Ficai… - Current Organic …, 2014 - ingentaconnect.com
Silver is a well known antimicrobial agent against a wide range of microorganisms–over 650
microorganisms from different classes, such as gram-positive and gram-negative bacteria …

Fabrication and cytotoxicity of gemcitabine-functionalized magnetite nanoparticles

RC Popescu, E Andronescu, BȘ Vasile, R Truşcă… - Molecules, 2017 - mdpi.com
Nanotechnology has been successfully used for the fabrication of targeted anti-cancer drug
carriers. This study aimed to obtain Fe3O4 nanoparticles functionalized with Gemcitabine to …

Magnetite nanoparticles for functionalized textile dressing to prevent fungal biofilms development

I Anghel, AM Grumezescu, E Andronescu… - Nanoscale research …, 2012 - Springer
The purpose of this work was to investigate the potential of functionalized magnetite
nanoparticles to improve the antibiofilm properties of textile dressing, tested in vitro against …

Synthesis, characterization and in vitro assessment of the magnetic chitosan–carboxymethylcellulose biocomposite interactions with the prokaryotic and eukaryotic …

AM Grumezescu, E Andronescu, A Ficai… - International journal of …, 2012 - Elsevier
Preparation and characterization of CS/Fe3O4/CMC composite scaffolds including the
morphology, crystallinity, and the in vitro efficacy as antibiotic delivery vehicles as well as …

Water dispersible magnetite nanoparticles influence the efficacy of antibiotics against planktonic and biofilm embedded Enterococcus faecalis cells

MC Chifiriuc, AM Grumezescu, E Andronescu, A Ficai… - Anaerobe, 2013 - Elsevier
The objective of this study was to investigate the potential of magnetic nanoparticles to
potentiate, but also to accomplish a sustained and controlled drug release and subsequently …

Improved antibacterial activity of cephalosporins loaded in magnetic chitosan microspheres

CM Chifiriuc, AM Grumezescu, C Saviuc… - International journal of …, 2012 - Elsevier
During the present study, we have evaluated magnetic chitosan as a potential drug delivery
device, by specifically determining if chitosan could elute antibiotics in an active form that …

In vitro activity of the new water-dispersible Fe3O4@usnic acid nanostructure against planktonic and sessile bacterial cells

AM Grumezescu, AI Cotar, E Andronescu… - Journal of nanoparticle …, 2013 - Springer
A new water-dispersible nanostructure based on magnetite (Fe 3 O 4) and usnic acid (UA)
was prepared in a well-shaped spherical form by a precipitation method. Nanoparticles were …