Traumatic injuries of the knee joint result in a wide variety of pathomechanisms, which
contribute to the development of so-called posttraumatic osteoarthritis (PTOA). These …

Joint injuries are known to induce pathomechanisms that might lead to posttraumatic
osteoarthritis (PTOA). In this regard, statins with their pleiotropic effects could represent …

Transplantation of xenogenic porcine chondrocytes could represent a future strategy for the
treatment of human articular cartilage defects. Major obstacles are humoral and cellular …

The terminal complement complex (TCC) has been described as a potential driver in the
pathogenesis of posttraumatic osteoarthritis (PTOA). However, sublytic TCC deposition …

Posttraumatic osteoarthritis (PTOA) is a special form of OA, developing after joint injuries.
Except for some minor differences between the clinical characteristics of patients suffering …

The goal of this study was to develop, validate, and implement an image analysis framework
to automatically analyze chondrocytes in 3D image stacks of cartilage acquired using a …

Background Knee osteoarthritis (OA) is known to be a progressive degenerative disorder;
however, recent evidence suggests that inflammatory mediators contribute to cartilage …

Laboratory-based osteoarthritis (OA) research usually includes study of cartilage
degeneration that happens at the early disease stage. Microscopic-level imaging methods …

Effekte der Hypothermie auf inflammatorische und degradative Prozesse nach
Knorpeltrauma Hintergrund: Traumata sind ein Risikofaktor für die Entwicklung einer …