Liquid biopsy in endometrial cancer: new opportunities for personalized oncology

L Muinelo-Romay, C Casas-Arozamena… - International journal of …, 2018 - mdpi.com
The identification of new molecular targets and biomarkers associated with high risk of
recurrence and response to therapy represents one of the main clinical challenges in the …

Proteomic biomarkers for the detection of endometrial cancer

K Njoku, D Chiasserini, AD Whetton, EJ Crosbie - Cancers, 2019 - mdpi.com
Endometrial cancer is the leading gynaecological malignancy in the western world and its
incidence is rising in tandem with the global epidemic of obesity. Early diagnosis is key to …

Tissue-based proteomic profiling in patients with hyperplasia and endometrial cancer

K Akkour, IO Alanazi, AA Alfadda, H Alhalal, A Masood… - Cells, 2022 - mdpi.com
Uterine cancers are among the most prevalent gynecological malignancies, and
endometrial cancer (EC) is the most common in this group. This study used tissue-based …

Exosomes on endometrial cancer: a biomarkers treasure trove?

AG Sykaras, K Christofidis, E Politi, S Theocharis - Cancers, 2022 - mdpi.com
Simple Summary Endometrial cancer (EC) is one of the main causes of cancer-related death
among women. Despite the advances in gynecologic oncology, the incidence of EC is on …

Two dimensional-difference in gel electrophoresis (2D-DIGE) proteomic approach for the identification of biomarkers in endometrial cancer serum

B Ura, S Biffi, L Monasta, G Arrigoni, I Battisti… - Cancers, 2021 - mdpi.com
Simple Summary Endometrial cancer is the most common gynecologic malignancy arising
from the endometrium. Identification of serum biomarkers could be beneficial for its early …

Two-Dimensional Polyacrylamide Gel Electrophoresis Coupled with Nanoliquid Chromatography–Tandem Mass Spectrometry-Based Identification of Differentially …

M Jayathirtha, T Jayaweera, D Whitham… - International journal of …, 2023 - mdpi.com
The identification of new genes/proteins involved in breast cancer (BC) occurrence is widely
used to discover novel biomarkers and understand the molecular mechanisms of BC …

SWATH-MS analysis of FFPE tissues identifies stathmin as a potential marker of endometrial cancer in patients exposed to tamoxifen

L Janacova, J Faktor, L Capkova… - Journal of proteome …, 2020 - ACS Publications
A specific form of endometrial cancer (EC) can develop in breast cancer patients previously
treated with tamoxifen (ET), an antagonist of estrogen receptor (ER) that inhibits proliferation …

C11orf54 promotes DNA repair via blocking CMA-mediated degradation of HIF1A

J Tan, W Wang, X Liu, J Xu, Y Che, Y Liu, J Hu… - Communications …, 2023 - nature.com
C11orf54 is an ester hydrolase highly conserved across different species. C11orf54 has
been identified as a biomarker protein of renal cancers, but its exact function remains poorly …

miR‐145‐5p Inhibits the Proliferation, Migration, and Invasion of Esophageal Carcinoma Cells by Targeting ABRACL

S Fan, P Chen, S Li - BioMed Research International, 2021 - Wiley Online Library
Objective. The study is aimed at investigating the regulatory relationship between miR‐145‐
5p and ABRACL, and has tried at clarifying the mechanisms underlying the proliferation …

Human costars family protein ABRACL modulates actin dynamics and cell migration and associates with tumorigenic growth

BY Hsiao, CH Chen, HY Chi, PR Yen, YZ Yu… - International Journal of …, 2021 - mdpi.com
Regulation of cellular actin dynamics is pivotal in driving cell motility. During cancer
development, cells migrate to invade and spread; therefore, dysregulation of actin regulators …