Coincident with the tsunami of COVID-19–related publications, there has been a surge of
studies using real-world data, including those obtained from the electronic health record …

The 21st Century Cures Act passed by the United States Congress mandates the US Food
and Drug Administration to develop guidance to evaluate the use of real‐world evidence …

Background: Injury and illness surveillance, and epidemiological studies, are fundamental
elements of concerted efforts to protect the health of the athlete. To encourage consistency …

Studies that generate real-world evidence on the effects of medical products through
analysis of digital data collected in clinical practice provide key insights for regulators …

In alignment with the International Council of Harmonization's strategic goals, a public-
private consortium has developed a structured template for planning and reporting on the …

Importance Use of attention-deficit/hyperactivity disorder (ADHD) medications has increased
substantially over the past decades. However, the potential risk of cardiovascular disease …

OBJECTIVE To assess associations between current use of sodium–glucose cotransporter 2
inhibitors (SGLT2is), glucagon-like peptide 1 receptor agonists (GLP-1RAs), and their …

Importance COVID-19 has had devastating effects on the health and well-being of older
adult residents and health care professionals in nursing homes. Uncertainty about the …

Importance Although children mainly experience mild COVID-19 disease, hospitalization
rates are increasing, with limited understanding of underlying factors. There is an …

Pharmacoepidemiologic and pharmacoeconomic analysis of health care databases has
become a vital source of evidence to support health care decision making and efficient …