Review of 3D cell culture with analysis in microfluidic systems
A review with 105 references that analyzes the emerging research area of 3D cell culture in
microfluidic platforms with integrated detection schemes. Over the last several decades a …
microfluidic platforms with integrated detection schemes. Over the last several decades a …
Automation of mass spectrometric detection of analytes and related workflows: A review
The developments in mass spectrometry (MS) in the past few decades reveal the power and
versatility of this technology. MS methods are utilized in routine analyses as well as research …
versatility of this technology. MS methods are utilized in routine analyses as well as research …
A 3D human adipose tissue model within a microfluidic device
F Yang, A Carmona, K Stojkova, EIG Huitron, A Goddi… - Lab on a Chip, 2021 - pubs.rsc.org
An accurate in vitro model of human adipose tissue could assist in the study of adipocyte
function and allow for better tools for screening new therapeutic compounds. Cell culture …
function and allow for better tools for screening new therapeutic compounds. Cell culture …
Dynamic in vitro intestinal barrier model coupled to chip-based liquid chromatography mass spectrometry for oral bioavailability studies
MJC Santbergen, M Van der Zande, A Gerssen… - Analytical and …, 2020 - Springer
In oral bioavailability studies, evaluation of the absorption and transport of drugs and food
components across the intestinal barrier is crucial. Advances in the field of organ-on-a-chip …
components across the intestinal barrier is crucial. Advances in the field of organ-on-a-chip …
Adipose microtissue-on-chip: a 3D cell culture platform for differentiation, stimulation, and proteomic analysis of human adipocytes
Human fat tissue has evolved to serve as a major energy reserve. An imbalance between
energy intake and expenditure leads to an expansion of adipose tissue. Maintenance of this …
energy intake and expenditure leads to an expansion of adipose tissue. Maintenance of this …
3D printed microfluidic device for online detection of neurochemical changes with high temporal resolution in human brain microdialysate
This paper presents the design, optimisation and fabrication of a mechanically robust 3D
printed microfluidic device for the high time resolution online analysis of biomarkers in a …
printed microfluidic device for the high time resolution online analysis of biomarkers in a …
Microfluidic chip with integrated electrophoretic immunoassay for investigating cell–cell interactions
S Lu, CE Dugan, RT Kennedy - Analytical chemistry, 2018 - ACS Publications
Microfluidics have been used to create “body-on-chip” systems to mimic in vivo cellular
interactions with a high level of control. Most such systems rely on optical observation of …
interactions with a high level of control. Most such systems rely on optical observation of …
Cell analysis on chip-mass spectrometry
Benefit from the development of microfluidic chip and mass spectrometry, chip-mass
spectrometry (Chip-MS) has become an ambient platform for cell analysis. Microfluidic chip …
spectrometry (Chip-MS) has become an ambient platform for cell analysis. Microfluidic chip …
Online and in situ analysis of organs-on-a-chip
MJC Santbergen, M van Der Zande… - TrAC Trends in …, 2019 - Elsevier
Organ-on-a-chip technology is used to study biological processes that involve multiple cell
types and temporal changes like, homeostasis, metabolism and responses to chemical …
types and temporal changes like, homeostasis, metabolism and responses to chemical …
A fluidic isolation-assisted homogeneous-flow-pressure chip-solid phase extraction-mass spectrometry system for online dynamic monitoring of 25-hydroxyvitamin D3 …
N Xu, H Lin, S Lin, W Zhang, S Han… - Analytical …, 2021 - ACS Publications
It is well known that cell can response to various chemical and mechanical stimuli.
Therefore, flow pressure variation induced by sample loading and elution should be small …
Therefore, flow pressure variation induced by sample loading and elution should be small …