Treatment of rare factor deficiencies other than hemophilia

M Menegatti, F Peyvandi - Blood, The Journal of the American …, 2019 - ashpublications.org
The deficiency of fibrinogen, prothrombin, factor V (FV), FVII, FVIII, FIX, FX, FXI, and FXIII,
called rare coagulation disorders (RCDs), may result in coagulopathies leading to …

Factor XI deficiency

MD Lewandowska, JM Connors - Hematology/Oncology …, 2021 - hemonc.theclinics.com
Factor XI (FXI) deficiency (hemophilia C or Rosenthal disease) was first described in the
1950s by Rosenthal and colleagues 1 in four generations of a family experiencing bleeding …

Recent advances in use of fresh frozen plasma, cryoprecipitate, immunoglobulins, and clotting factors for transfusion support in patients with hematologic disease

PM Nair, MJ Rendo, KM Reddoch-Cardenas… - Seminars in …, 2020 - Elsevier
Hematologic diseases include a broad range of acquired and congenital disorders, many of
which affect plasma proteins that control hemostasis and immune responses. Therapeutic …

Factor XI deficiency: phenotypic age-related considerations and clinical approach towards bleeding risk assessment

AA Barg, T Livnat, G Kenet - Blood, 2024 - Elsevier
Factor XI (FXI) deficiency is a rare bleeding disorder that presents complex challenges in
patient assessment and bleeding risk management. Despite generally causing mild to …

The foundation for investigating factor XI as a target for inhibition in human cardiovascular disease

AE Ali, RC Becker - Journal of Thrombosis and Thrombolysis, 2024 - Springer
Anticoagulant therapy is a mainstay in the management of patients with cardiovascular
disease and related conditions characterized by a heightened risk for thrombosis. Acute …

The clinical management of factor XI deficiency in pregnant women

AP Wheeler, C Hemingway… - Expert review of …, 2020 - Taylor & Francis
ABSTRACT Introduction Factor XI (FXI) deficiency is associated with highly variable
bleeding, including excessive gynecologic and obstetrical bleeding. Since approximately …

[HTML][HTML] Hemophilia C: a case report with updates on diagnosis and management of a rare bleeding disorder

T Jayakrishnan, D Shah, P Mewawalla - Journal of Hematology, 2019 - ncbi.nlm.nih.gov
Hemophilia C or factor XI deficiency is a rare clotting disorder with prevalence of only 1 per 1
million. A 24-year-old male with multiple abdominal surgeries complicated by wound …

Indications for the use of therapeutic plasma in adult patients

C Von Heymann, H Lier, C Rosenthal… - Transfusion Medicine …, 2023 - karger.com
Background: Different preparations for therapeutic plasma are available on the market. The
German hemotherapy guideline has been completely updated in 2020 and, for this purpose …

Challenges of antithrombotic therapy in the management of cardiovascular disease in patients with inherited bleeding disorders: A single‐centre experience

OC Cohen, M Bertelli, G Manmathan, C Little… - …, 2021 - Wiley Online Library
Introduction Cardiovascular events in patients with inherited bleeding disorders are
challenging to manage. The risk of bleeding secondary to antithrombotic treatment must be …

Coagulation management in obstetric anesthesia

MI Lumbreras-Marquez, D Villela-Franyutti… - Current Anesthesiology …, 2022 - Springer
Abstract Purpose of Review Management of coagulation in pregnancy requires a
multidisciplinary and dynamic approach by obstetric anesthesiologists, obstetricians, and …