Heart failure and cardiovascular disorders represent the leading cause of death in diabetic
patients. Here we present a systematic review of the main mechanisms underlying the …

The molecular pathways contributing to visual signal transduction in the retina generate a
high energy demand that has functional and structural consequences such as …

Changes in cellular free Zn2+ concentration, including those in the sarco (endo) plasmic
reticulum [S (E) R], are primarily coordinated by Zn2+ transporters (ZnTs) whose identity and …

Aging in humans represents declining in cardio-protective systems, however its mechanisms
are not known yet. We aimed to analyse how aging affects key mechanisms responsible for …

Functional contribution of S (E) R-mitochondria coupling to normal cellular processes is
crucial and any alteration in S (E) R-mitochondria axis may be responsible for the onset of …

Zinc has been considered as a vital constituent of proteins, including enzymes. Mobile
reactive zinc (Zn2+) is the key form of zinc involved in signal transductions, which are mainly …

Scope Garcinia cambogia (G. cambogia) is known to have antiobesity effects. In this study,
the therapeutic effects of G. cambogia on glucose homeostasis in obesity‐induced diabetes …

This review is aimed at providing an overview of the key hallmarks of cardiomyocytes in
physiological and pathological conditions. The main feature of cardiac tissue is the force …

Zinc plays an important role in biological systems as bound and histochemically reactive
labile Zn2+. Although Zn2+ concentration is in the nM range in cardiomyocytes at rest and …

Sodium-glucose cotransporter 2 (SGLT2) inhibitors showed significant effects in patients
with diabetes or metabolic syndrome (MetS) with high cardiovascular risk. Although the …