[HTML][HTML] Lipid and lipoprotein dysregulation in sepsis: Clinical and mechanistic insights into chronic critical illness

G Barker, C Leeuwenburgh, T Brusko… - Journal of clinical …, 2021 - mdpi.com
In addition to their well-characterized roles in metabolism, lipids and lipoproteins have
pleiotropic effects on the innate immune system. These undergo clinically relevant …

[HTML][HTML] Epidemiology of sepsis in Brazil: Incidence, lethality, costs, and other indicators for Brazilian Unified Health System hospitalizations from 2006 to 2015

RA Quintano Neira, S Hamacher, AM Japiassu - PloS one, 2018 - journals.plos.org
Background Sepsis is considered a major worldwide health burden, with high mortality and
associated costs. Health indicators are essential to define strategies to improve the …

Predictive accuracy of the quick sepsis-related organ failure assessment score in Brazil. A prospective multicenter study

FR Machado, AB Cavalcanti, MB Monteiro… - American journal of …, 2020 - atsjournals.org
Rationale: Although proposed as a clinical prompt to sepsis based on predictive validity for
mortality, the Quick Sepsis-related Organ Failure Assessment (qSOFA) score is often used …

[HTML][HTML] Cuminaldehyde potentiates the antimicrobial actions of ciprofloxacin against Staphylococcus aureus and Escherichia coli

V Monteiro-Neto, CD de Souza, LF Gonzaga… - PLoS …, 2020 - journals.plos.org
Escherichia coli and Staphylococcus aureus are important agents of urinary tract infections
that can often evolve to severe infections. The rise of antibiotic-resistant strains has driven …

[HTML][HTML] Branched-chain amino acids can predict mortality in ICU sepsis patients

AC Reisinger, F Posch, G Hackl, G Marsche, H Sourij… - Nutrients, 2021 - mdpi.com
Sepsis biomarkers and potential therapeutic targets are urgently needed. With proton
nuclear magnetic resonance (1H NMR) spectroscopy, several metabolites can be assessed …

[HTML][HTML] Global trends in the awareness of sepsis: insights from search engine data between 2012 and 2017

CS Jabaley, JM Blum, RF Groff, VN O'Reilly-Shah - Critical Care, 2018 - Springer
Background Sepsis is an established global health priority with high mortality that can be
curtailed through early recognition and intervention; as such, efforts to raise awareness are …

Immunophenotyping of monocytes during human sepsis shows impairment in antigen presentation: a shift toward nonclassical differentiation and upregulation of …

NVF da Mota, MKC Brunialti, SS Santos, FR Machado… - Shock, 2018 - journals.lww.com
Monocytes and macrophages are pivotal in the host response to sepsis, recognizing the
infecting microorganism and triggering an inflammatory response. These functions are, at …

[HTML][HTML] Assessment of implementation methods in sepsis: study protocol for a cluster-randomized hybrid type 2 trial

HE Frank, L Evans, G Phillips, RP Dellinger… - Trials, 2023 - Springer
Background Sepsis is the leading cause of intensive care unit (ICU) admission and ICU
death. In recognition of the burden of sepsis, the Surviving Sepsis Campaign (SSC) and the …

The value of biomarker-guided antibiotic therapy

E Haag, A Molitor, C Gregoriano, B Mueller… - Expert review of …, 2020 - Taylor & Francis
Introduction There is an increasing interest to individualize patient management and
decisions regarding antibiotic treatment. Biomarkers may provide relevant information for …

Highly visible sepsis publications from 2012 to 2017: Analysis and comparison of altmetrics and bibliometrics

CS Jabaley, RF Groff IV, MJ Stentz, V Moll… - Journal of critical …, 2018 - Elsevier
Purpose: We sought to delineate highly visible publications related to sepsis. Within these
subsets, elements of altmetrics performance, including mentions on Twitter, and the …