The development of alcohol use disorder (AUD) involves binge or heavy drinking to high
levels of intoxication that leads to compulsive intake, the loss of control in limiting intake, and …

Sleep abnormalities are associated with acute and chronic use of addictive substances.
Although sleep complaints associated with use and abstinence from addictive substances …

Sleep‐related complaints are widely prevalent in those with alcohol dependence (AD). AD is
associated not only with insomnia, but also with multiple sleep‐related disorders as a …

Substance use disorders (SUD) are common and individuals who suffer from them are
prone to relapse. One of the most common consequences of the use of and withdrawal from …

Insomnia in patients with alcohol dependence has increasingly become a target of treatment
due to its prevalence, persistence, and associations with relapse and suicidal thoughts, as …

Agomelatine, a melatonergic antidepressant with a rapid onset of action, is one of the most
recent drugs in the antidepressant category. Agomelatine's antidepressant actions are …

Introduction: Insomnia has been implicated in the development, maintenance, worsening,
and relapse of alcohol use disorder (AUD). Areas covered: The authors review the possible …

Melatonin is a pleiotropic signalling molecule that regulates several physiological functions,
and synchronises biological rhythms. Recent evidences are beginning to reveal that a …

Despite major advances in the understanding about ethanol actions, the precise underlying
neurobiological mechanisms for ethanol dependence remain largely elusive. We recently …

A high percentage of subjects diagnosed with alcohol use disorder (AUD) suffer from
sleeping difficulties. Lack of sleep could lead AUD patients to relapse or, sometimes, to …