[HTML][HTML] Solid lipid nanoparticles for drug delivery: pharmacological and biopharmaceutical aspects

S Scioli Montoto, G Muraca, ME Ruiz - Frontiers in molecular …, 2020 - frontiersin.org
In the golden age of pharmaceutical nanocarriers, we are witnessing a maturation stage of
the original concepts and ideas. There is no doubt that nanoformulations are extremely …

Sulfated seaweed polysaccharides as multifunctional materials in drug delivery applications

L Cunha, A Grenha - Marine drugs, 2016 - mdpi.com
In the last decades, the discovery of metabolites from marine resources showing biological
activity has increased significantly. Among marine resources, seaweed is a valuable source …

Anionic nanoparticles enable the oral delivery of proteins by enhancing intestinal permeability

NG Lamson, A Berger, KC Fein… - Nature biomedical …, 2020 - nature.com
The oral delivery of bioactive peptides and proteins is prevented by the intestinal epithelial
barrier, in which intercellular tight junction complexes block the uptake of macromolecules …

[HTML][HTML] Changes in intestinal tight junction permeability associated with industrial food additives explain the rising incidence of autoimmune disease

A Lerner, T Matthias - Autoimmunity reviews, 2015 - Elsevier
The incidence of autoimmune diseases is increasing along with the expansion of industrial
food processing and food additive consumption. The intestinal epithelial barrier, with its …

[HTML][HTML] Surface design of nanocarriers: Key to more efficient oral drug delivery systems

H Spleis, M Sandmeier, V Claus… - Advances in colloid and …, 2023 - Elsevier
As nanocarriers (NCs) can improve the solubility of drugs, prevent their degradation by
gastrointestinal (GI) enzymes and promote their transport across the mucus gel layer and …

Advances in nutraceutical delivery systems: From formulation design for bioavailability enhancement to efficacy and safety evaluation

RFS Gonçalves, JT Martins, CMM Duarte… - Trends in Food Science …, 2018 - Elsevier
Background Aiming at the enhancement of food products' nutritional and health value, the
incorporation of nutraceuticals has attracted increasing interest in the last years. However …

Biofunctionalization of nanoceria with sperminated hyaluronan enhances drug delivery performance for corneal alkali burn therapy

TY Ger, CJ Yang, S Ghosh, JY Lai - Chemical Engineering Journal, 2023 - Elsevier
Corneal alkali burn (AB) injury is the most common sight-threatening injury that is highly
associated with oxidative stress, inflammation, apoptosis, angiogenesis, and cell deficiency …

Engineering the drug carrier biointerface to overcome biological barriers to drug delivery

JA Finbloom, F Sousa, MM Stevens… - Advanced drug delivery …, 2020 - Elsevier
Micro and nanoscale drug carriers must navigate through a plethora of dynamic biological
systems prior to reaching their tissue or disease targets. The biological obstacles to drug …

Fucoidan-based, tumor-activated nanoplatform for overcoming hypoxia and enhancing photodynamic therapy and antitumor immunity

CH Chung, KY Lu, WC Lee, WJ Hsu, WF Lee, JZ Dai… - Biomaterials, 2020 - Elsevier
Multifunctional nanoplatforms combined with photodynamic therapy (PDT) and anticancer
drugs have shown great promising in cancer therapy. However, their efficacy is limited by …

Marine polysaccharides in pharmaceutical applications: Fucoidan and chitosan as key players in the drug delivery match field

AI Barbosa, AJ Coutinho, SA Costa Lima, S Reis - Marine Drugs, 2019 - mdpi.com
The use of marine-origin polysaccharides has increased in recent research because they
are abundant, cheap, biocompatible, and biodegradable. These features motivate their …