In recent decades, researchers around the world have been studying intensively how micro-
organisms that are present inside living organisms could affect the main processes of life …

Abstract Food allergy is affecting 5–8% of young children and 2–4% of adults and seems to
be increasing in prevalence. The cause of the increase in food allergy is largely unknown …

Aging impairs the capacity to respond to novel antigens, reducing immune protection
against pathogens and vaccine efficacy. Dietary restriction (DR) extends life-and health …

Centrosomes are the primary microtubule organizer in eukaryotic cells. In addition to
shaping the intracellular microtubule network and the mitotic spindle, centrosomes are …

The extent to which AIRRs differ among and within individuals remains elusive. Via ultra-
deep repertoire sequencing of 22 and 25 tissues in three cynomolgus macaques …

Emerging evidence indicates that perinatal infection and inflammation can influence the
developing immune system and may ultimately affect long-term health and disease …

Enteric infectious diseases account for more than a billion disease episodes yearly
worldwide resulting in approximately 2 million deaths, with children under 5 years old and …

Tissue resident (TR) immune cells play important roles in facilitating tissue homeostasis,
coordinating immune responses against infections and tumors, and maintaining …

Targeting immune checkpoints is a well-established strategy in cancer therapy, and
antibodies blocking PD-1/PD-L1 interactions to restore the immunological activity against …

HIV and parasite infections accelerate biological aging, resulting in immune senescence,
apoptosis and cellular damage. Telomere length is considered to be one of the most …