▪ Abstract About 40% of patients undergoing maintenance dialysis suffer from varying
degrees of protein-energy malnutrition. This is a problem of substantial importance because …

In this review we summarize the findings from the literature and our own laboratory on the
decreased PON1 activity in renal failure, the mechanisms proposed and the effect of …

Paraoxonase (PON1) is principally complexed to HDL and is responsible, at least in part, for
its antioxidant properties. PON1 activity decreases in several pathologies associated with …

Aim. To determine whether paraoxonase activity, paraoxonase phenotypes, and lipid status
are altered in uremic patients on long-term hemodialysis treatment as compared to healthy …

Background Paraoxonase (PON1) is a high-density lipoprotein (HDL)-associated enzyme
and has been shown to reduce the susceptibility of low-density lipoprotein (LDL) to lipid …

Objective High-density lipoprotein (HDL)-associated antioxidant paraoxonase (PON) may
reduce low-density lipoprotein (LDL) oxidation and prevent atherosclerosis. The aim of this …

The incidence of atherosclerosis increases with age. Oxidative changes in proteins and
lipids are considered to be among the molecular mechanisms leading to endothelial …

The purpose of the present study was to investigate the distribution of PON1 Q192R and
L55M polymorphisms and activities in a North African population and to determine their …

Background Cardiovascular disease causes morbidity and mortality in chronic kidney
disease. Increased formation of oxygen-derived radicals can accelerate the development of …

Soy protein favorably alters serum lipids and lipoproteins in hypercholesterolemic
individuals, thereby reducing cardiovascular disease risk. The primary purpose was to …